Molecular epidemiologic studies of tuberculosis (TB) have focused largely on utilizing
molecular techniques to address short-and long-term epidemiologic questions, such as in …

DNA fingerprinting has attracted considerable interest as means for identifying, tracing and
preventing the dissemination of infectious agents. Various methods have been developed …

Molecular typing based on 12 loci containing variable numbers of tandem repeats of
mycobacterial interspersed repetitive units (MIRU-VNTRs) has been adopted in combination …

Abstract Background The Direct Repeat locus of the Mycobacterium tuberculosis complex
(MTC) is a member of the CRISPR (Clustered regularly interspaced short palindromic …

Tuberculosis is an ever-changing field. The editors and authors of “Tuberculosis 2007–from
basic science to patient care” have made every effort to provide information that is accurate …

Objectives To compare mutations in the quinolone resistance-determining region of the gyrA
gene and flanking sequences with the MICs of ofloxacin and moxifloxacin for Mycobacterium …

Background Studies on recurrent tuberculosis (TB), TB molecular epidemiology and drug
susceptibility testing rely on the analysis of one Mycobacterium tuberculosis isolate from a …

Recent advances in genomics and molecular biology are providing an excellent opportunity
to get a glimpse into the past, to examine the present, and to predict the future evolution of …

Tuberculosis (TB) is a contagious disease with a complex epidemiology. Therefore,
molecular typing (genotyping) of Mycobacterium tuberculosis complex (MTBC) strains is of …

Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique
spoligotype signatures specifically associated with IS 6110-defined strain families …