For decades, mesenchymal stem (MSCs) cells have been used for cardiovascular diseases
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …

The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

Mechanisms behind how the immune system signals to the brain in response to systemic
inflammation are not fully understood. Transgenic mice expressing Cre recombinase …

We previously reported that microRNA (miRNA) is present in human breast milk. Recently,
other groups have reported that bovine milk also contains miRNA; however, these reports …

Helminth parasites are masters at manipulating host immune responses, using an array of
sophisticated mechanisms. One of the major mechanisms enabling helminths to establish …

Malignant cells express ligands for the natural killer cell immunoreceptor NKG2D, which
sensitizes to early recognition and elimination by cytotoxic lymphocytes and provides an …

Background MicroRNAs (miRNAs or miRs) participate in the regulation of several biological
processes, including cell differentiation. Recently, miR-34a has been implicated in the …

In recent years it has been shown that the therapeutic benefits of human mesenchymal
stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to …

Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system
(CNS). Despite a complex pathogenesis, it appears that an imbalanced immune system …

Background: p53 plays an important role in many areas of cellular physiology and biology,
ranging from cellular development and differentiation to cell cycle arrest and apoptosis …