[HTML][HTML] Epigenetic regulation in gastroenteropancreatic neuroendocrine tumors

JS Crabtree - Frontiers in Oncology, 2022 - frontiersin.org
Gastroenteropancreatic neuroendocrine neoplasms are a rare, diverse group of
neuroendocrine tumors that form in the pancreatic and gastrointestinal tract, and often …

The uprise of RNA biology in neuroendocrine neoplasms: altered splicing and RNA species unveil translational opportunities

R Blázquez-Encinas, MT Moreno-Montilla… - Reviews in Endocrine …, 2023 - Springer
Neuroendocrine neoplasms (NENs) comprise a highly heterogeneous group of tumors
arising from the diffuse neuroendocrine system. NENs mainly originate in gastrointestinal …

Circ_0001367 inhibits glioma proliferation, migration and invasion by sponging miR-431 and thus regulating NRXN3

L Liu, P Zhang, X Dong, H Li, S Li, S Cheng… - Cell Death & …, 2021 - nature.com
Many studies have reported that circular RNAs play a vital role in the malignant progression
of human cancers. However, the role and underlying mechanism of circRNAs in the …

Pancreatic neuroendocrine neoplasms: updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classification

H Ishida, AK Lam - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (PanNENs) are the neuroendocrine neoplasms with
greatest rate of increase in incidence. Approximately 10% of PanNENs arise as inherited …

High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer

A Lin, J Feng, X Chen, D Wang, M Wong, G Zhang… - Cancer letters, 2021 - Elsevier
Pancreatic cancer has the lowest survival rate out of all types of cancer. Pancreatic cancer
patients are often diagnosed at advanced stages, hence an urgent need for a better …

A novel 7‑hypoxia‑related long non‑coding RNA signature associated with prognosis and proliferation in melanoma

Y Luo, T Li, H Zhao, A Chen - Molecular medicine …, 2022 - spandidos-publications.com
Hypoxia‑related long non‑coding RNAs (lncRNAs) are important indicators of the poor
prognosis of cancers. The present study aimed to explore the potential relationship between …

Current and New Challenges in the Management of Pancreatic Neuroendocrine Tumors: The Role of miRNA-Based Approaches as New Reliable Biomarkers

A Havasi, D Sur, SS Cainap, CV Lungulescu… - International Journal of …, 2022 - mdpi.com
Pancreatic neuroendocrine tumors (PanNETs) are rare tumors; however, their incidence
greatly increases with age, and they occur more frequently among the elderly. They …

Cutting the brakes on ras—cytoplasmic GAPs as targets of inactivation in cancer

A Bellazzo, L Collavin - Cancers, 2020 - mdpi.com
Simple Summary GTPase-Activating Proteins (RasGAPs) are a group of structurally related
proteins with a fundamental role in controlling the activity of Ras in normal and cancer cells …

Circ_0049447 acts as a tumor suppressor in gastric cancer through reducing proliferation, migration, invasion, and epithelial-mesenchymal transition

KW Tang, ZX Guo, ZH Wu, C Zhou, J Sun… - Chinese Medical …, 2021 - mednexus.org
Background: Although increasing abnormal expression of circular RNAs (circRNAs) has
been revealed in various cancers, there were a small number of studies about circRNAs in …

Identification of circRNA circ-CSPP1 as a potent driver of colorectal cancer by directly targeting the miR-431/LASP1 axis

M Li, J Zhuang, D Kang, Y Chen, W Song - Open Life Sciences, 2021 - degruyter.com
Colorectal cancer (CRC) is the third most common malignancy worldwide. Circular RNAs
(circRNAs) have been implicated in cancer biology. The purpose of the current work is to …