Treating cancer with microRNA replacement therapy: A literature review
N Hosseinahli, M Aghapour, PHG Duijf… - Journal of cellular …, 2018 - Wiley Online Library
microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …
MicroRNA key to angiogenesis regulation: MiRNA biology and therapy
Angiogenesis is involved in maintaining normal physiological processes like embryonic
development, wound healing, inflammation and reproduction. Pathogenesis of various …
development, wound healing, inflammation and reproduction. Pathogenesis of various …
Therapeutic targeting of non-coding RNAs in cancer
O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …
Targeting microRNAs in cancer: rationale, strategies and challenges
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …
Recent trends in targeting miRNAs for cancer therapy
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
[HTML][HTML] miR-34: from bench to bedside
M Agostini, RA Knight - Oncotarget, 2014 - ncbi.nlm.nih.gov
The mir-34 family was originally cloned and characterized in 2007 as a p53 target gene.
Almost immediately it became clear that its major role is as a master regulator of tumor …
Almost immediately it became clear that its major role is as a master regulator of tumor …
Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
During recent decades there have been remarkable advances and profound changes in
cancer therapy. Many therapeutic strategies learned at the bench, including monoclonal …
cancer therapy. Many therapeutic strategies learned at the bench, including monoclonal …
Recent advances in microfluidics for the preparation of drug and gene delivery systems
Drug delivery systems (DDSs) have great potential for improving the treatment of several
diseases, especially microbial infections and cancers. However, the formulation procedures …
diseases, especially microbial infections and cancers. However, the formulation procedures …
MicroRNA regulation in angiogenesis
A Caporali, C Emanueli - Vascular pharmacology, 2011 - Elsevier
The term angiogenesis derives from the Greek words' angeio'meaning blood vessel,
and'genesis' meaning production or birth, together referring to the creation of blood vessels …
and'genesis' meaning production or birth, together referring to the creation of blood vessels …
Liposomes: versatile and biocompatible nanovesicles for efficient biomolecules delivery
Since the revolutionary discovery that phospholipids can form closed bilayered structures in
aqueous systems, liposomes have become a very interesting topic of research. Because of …
aqueous systems, liposomes have become a very interesting topic of research. Because of …