Treating cancer with microRNA replacement therapy: A literature review

N Hosseinahli, M Aghapour, PHG Duijf… - Journal of cellular …, 2018 - Wiley Online Library
microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …

MicroRNA key to angiogenesis regulation: MiRNA biology and therapy

A Tiwari, B Mukherjee, M Dixit - Current cancer drug targets, 2018 - ingentaconnect.com
Angiogenesis is involved in maintaining normal physiological processes like embryonic
development, wound healing, inflammation and reproduction. Pathogenesis of various …

Therapeutic targeting of non-coding RNAs in cancer

O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …

Targeting microRNAs in cancer: rationale, strategies and challenges

R Garzon, G Marcucci, CM Croce - Nature reviews Drug discovery, 2010 - nature.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …

Recent trends in targeting miRNAs for cancer therapy

V Shah, J Shah - Journal of Pharmacy and Pharmacology, 2020 - academic.oup.com
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …

[HTML][HTML] miR-34: from bench to bedside

M Agostini, RA Knight - Oncotarget, 2014 - ncbi.nlm.nih.gov
The mir-34 family was originally cloned and characterized in 2007 as a p53 target gene.
Almost immediately it became clear that its major role is as a master regulator of tumor …

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy

E Miele, GP Spinelli, E Miele, E Di Fabrizio… - International journal …, 2012 - Taylor & Francis
During recent decades there have been remarkable advances and profound changes in
cancer therapy. Many therapeutic strategies learned at the bench, including monoclonal …

Recent advances in microfluidics for the preparation of drug and gene delivery systems

MA Tomeh, X Zhao - Molecular Pharmaceutics, 2020 - ACS Publications
Drug delivery systems (DDSs) have great potential for improving the treatment of several
diseases, especially microbial infections and cancers. However, the formulation procedures …

MicroRNA regulation in angiogenesis

A Caporali, C Emanueli - Vascular pharmacology, 2011 - Elsevier
The term angiogenesis derives from the Greek words' angeio'meaning blood vessel,
and'genesis' meaning production or birth, together referring to the creation of blood vessels …

Liposomes: versatile and biocompatible nanovesicles for efficient biomolecules delivery

S Mallick, JS Choi - Journal of nanoscience and …, 2014 - ingentaconnect.com
Since the revolutionary discovery that phospholipids can form closed bilayered structures in
aqueous systems, liposomes have become a very interesting topic of research. Because of …