[HTML][HTML] Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials

I Jantan, W Ahmad, SNA Bukhari - Frontiers in plant science, 2015 - frontiersin.org
The phagocyte–microbe interactions in the immune system is a defense mechanism but
when excessively or inappropriately deployed can harm host tissues and participate in the …

Health functionality of apigenin: A review

F Ali, Rahul, F Naz, S Jyoti… - International Journal of …, 2017 - Taylor & Francis
Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

Modifications of dietary flavonoids towards improved bioactivity: An update on structure–activity relationship

L Chen, H Teng, Z Xie, H Cao, WS Cheang… - Critical reviews in …, 2018 - Taylor & Francis
Over the past two decades, extensive studies have revealed that inflammation represents a
major risk factor for various human diseases. Chronic inflammatory responses predispose to …

Hydroxylation decoration patterns of flavonoids in horticultural crops: Chemistry, bioactivity, and biosynthesis

Y Liu, J Qian, J Li, M Xing, D Grierson… - Horticulture …, 2022 - academic.oup.com
Flavonoids are the most widespread polyphenolic compounds and are important dietary
constituents present in horticultural crops such as fruits, vegetables, and tea. Natural …

[HTML][HTML] Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin

G Seelinger, I Merfort, CM Schempp - Planta medica, 2008 - thieme-connect.com
Luteolin is a flavone which occurs in medicinal plants as well as in some vegetables and
spices. It is a natural anti-oxidant with less pro-oxidant potential than the flavonol quercetin …

An overview on immunoregulatory and anti-inflammatory properties of chrysin and flavonoids substances

M Zeinali, SA Rezaee, H Hosseinzadeh - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Inflammation and the pro-inflammatory cytokines are associated with numerous chronic
diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from …

The role of quercetin, flavonols and flavones in modulating inflammatory cell function

S Chirumbolo - Inflammation & Allergy-Drug Targets (Formerly …, 2010 - ingentaconnect.com
Flavonoids are polyphenolic substances derived from plants that play several
pharmacological activities. They possess anti-viral, anti-microbial, anti-inflammatory and anti …

In vitro anti-inflammatory properties of honey flavonoids: A review

B Silva, FC Biluca, LV Gonzaga, R Fett… - Food research …, 2021 - Elsevier
Honey is a natural ready-to-eat product rich in flavonoids, which is known by the wound
healing properties due to both antibacterial and antioxidant activity. Flavonoids mitigate …

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds

W Chanput, J Mes, RAM Vreeburg, HFJ Savelkoul… - Food & function, 2010 - pubs.rsc.org
An assay was developed to study inflammation-related immune responses of food
compounds on monocytes and macrophages derived from THP-1 cell line. First strategy …

[HTML][HTML] Inflammaging as a prodrome to Alzheimer's disease

B Giunta, F Fernandez, WV Nikolic, D Obregon… - Journal of …, 2008 - Springer
Recently, the term" inflammaging" was coined by Franceshci and colleagues to characterize
a widely accepted paradigm that ageing is accompanied by a low-grade chronic up …