Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …

Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Pyroptosis refers to the process of gasdermin-mediated lytic programmed cell death (PCD)
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …

Pyroptosis is an inflammatory form of programmed cell death (PCD) that is regulated by the
Gasdermin protein family in response to various stimuli, playing a critical role in the …

The alternations in the hypoxic and immune microenvironment are closely related to the
therapeutic effect and prognosis of oral squamous cell carcinoma (OSCC). Herein, a new …

Pyroptosis is a newly discovered inflammatory form of programmed cell death, which
promotes systemic immune response in cancer immunotherapy. GSDMD is one of the key …

Recurrent spontaneous abortion (RSA) is a common complication of pregnancy that affects
the physical and mental health of pregnant women, and approximately 50% of the …

Hexokinase 2 (HK2) is the principal rate-limiting enzyme in the aerobic glycolysis pathway
and determines the quantity of glucose entering glycolysis. However, the current HK2 …

Inducing pyroptosis in cancer cells can result in a strong anti-tumor immune response. Our
preliminary study indicates that pyroptosis can be temporarily strengthened by disrupting …

Abstract Environmental Benzo (a) pyrene (BaP) and its ultimate metabolite BPDE (benzo (a)
pyrene-7, 8-dihydrodiol-9, 10-epoxide) are typical persistent organic pollutants and …