Insulin signal transduction perturbations in insulin resistance

M Khalid, J Alkaabi, MAB Khan, A Adem - International journal of …, 2021 - mdpi.com
Type 2 diabetes mellitus is a widespread medical condition, characterized by high blood
glucose and inadequate insulin action, which leads to insulin resistance. Insulin resistance …

The role of insulin resistance and diabetes in nonalcoholic fatty liver disease

H Fujii, N Kawada… - International journal of …, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) consists of the entire spectrum of fatty liver disease
in patients without significant alcohol consumption, ranging from nonalcoholic fatty liver …

Acute hypoxia changes the mode of glucose and lipid utilization in the liver of the largemouth bass (Micropterus salmoides)

JL Sun, LL Zhao, H Wu, Q Liu, L Liao, J Luo… - Science of the Total …, 2020 - Elsevier
Dissolved oxygen (DO) undountedly affects fish distribution, metabolism, and evern survival.
Intensive aquaculture and environmental changes will inevitably lead to hypoxic stress for …

FGF19 protects skeletal muscle against obesity‐induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT‐1/PGC‐α pathway

A Guo, K Li, HC Tian, Z Fan, QN Chen… - Journal of Cellular …, 2021 - Wiley Online Library
Obesity is associated with biological dysfunction in skeletal muscle. As a condition of obesity
accompanied by muscle mass loss and physical dysfunction, sarcopenic obesity (SO) has …

Ethnopharmacological, Phytochemical, Pharmacological, and Toxicological Review on Senna auriculata (L.) Roxb.: A Special Insight to Antidiabetic Property

GC Nille, SK Mishra, AK Chaudhary… - Frontiers in …, 2021 - frontiersin.org
Avartaki (Senna auriculata (L.) Roxb. syn. Cassia auriculata L.; Family-Fabaceae) is a
traditional medicinal plant, widely used for the treatment of various ailments in Ayurveda and …

Bisphenol A and type 2 diabetes mellitus: a review of epidemiologic, functional, and early life factors

F Farrugia, A Aquilina, J Vassallo, NP Pace - International journal of …, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is characterised by insulin resistance and eventual
pancreatic β-cell dysfunction, resulting in persistent high blood glucose levels. Endocrine …

[HTML][HTML] Evaluation of antidiabetic activity of bud and flower of Avaram Senna (Cassia auriculata L.) In high fat diet and streptozotocin induced diabetic rats

G Nambirajan, K Karunanidhi, A Ganesan… - Biomedicine & …, 2018 - Elsevier
Abstract Type 2 Diabetes Mellitus (T2DM) is very common metabolic disorder affecting
people of all age groups. The change in life style and environmental factors are the …

The structures of two polysaccharides from Angelica sinensis and their effects on hepatic insulin resistance through blocking RAGE

W Liu, Z Li, C Feng, S Hu, X Yang, K Xiao, Q Nong… - Carbohydrate …, 2022 - Elsevier
This study found two novel homogeneous polysaccharides from Angelica sinensis, APS-1I
and APS-2II, binding to RAGE with a dissociation constant of 2.02±0.2 and 85.92±0.2 μM …

HIIT ameliorates inflammation and lipid metabolism by regulating macrophage polarization and mitochondrial dynamics in the liver of type 2 diabetes mellitus mice

Y Wang, Y Guo, Y Xu, W Wang, S Zhuang, R Wang… - Metabolites, 2022 - mdpi.com
High-intensity interval training (HIIT), a new type of exercise, can effectively prevent the
progression of metabolic diseases. The aim of this study was to investigate the effects of HIIT …

Recent updates on targeting the molecular mediators of NAFLD

J Wang, L Wang, XJ Zhang, P Zhang, J Cai… - Journal of Molecular …, 2023 - Springer
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common disease
worldwide in an era of rapid economic growth. NAFLD is a multifactorial disease, involving …