Much success has been achieved with platinum-based chemotherapeutic agents, ie through
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …

Ofele and Wanzlick reported the synthesis of the first N-heterocyclic carbene (NHC)-metal
complexes in 1968. 1, 2 The isolation of the first free carbene by Arduengo in 1991 set the …

This book helps readers understand the fundamental principles and phenomena that control
the transfer of trace elements. It describes the occurrence and behavior of trace elements in …

The clinical success of cisplatin and its derivatives has had an enormous impact on the
discovery of novel metal-based drugs. Extensive studies have focused on the interaction of …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

There is a need for new, safer, and more effective agents to treat cancer. Cytostatics that
have transition metals at their core have attracted renewed interest from scientists …

This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

The first mixed ligand Mn (II) and Cd (II) complexes containing 4‐methoxy‐pyridine‐2‐
carboxylic acid (4‐mpic) and 4, 4′‐dimethyl‐2, 2′‐bipyridine (dmbpy) were synthesized in …

A novel series of Zn 2+, Cd 2+ and UO 2 2+ complexes of ligands namely 1-[(5-mercapto-1H-
1, 2, 4-triazole-3-ylimino) methyl] naphthalene-2-ol (HL 1) and [(1H-1, 2, 4-triazole-3-ylimino) …

Platinum complexes which are most studied metal complexes due to their importance as
adjuvant therapy of cancers aiming to induce tumor-cell-death. Some of the platinum-based …