It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Chemical exchange saturation transfer (CEST) is a relatively new contrast mechanism for
MRI. CEST MRI exploits a specific MR frequency (chemical shift) of a molecule while …

Chiral sensors have attracted growing interest due to their application in health monitoring.
However, rational design of wearable logic chiral sensors remains a great challenge. In this …

Altered metabolism is considered a core hallmark of cancer. By monitoring in vivo
metabolites changes or characterizing the tumor microenvironment, non-invasive imaging …

Due to the implication of altered metabolism in a large spectrum of tissue function and
disease, assessment of metabolic processes becomes essential in managing health. In this …

A new potential ZnII responsive MnII-based MRI CA candidate derived from pyclen-3, 9-
diacetate (3, 9-PC2A) has been synthesized and it possesses a di-(2-picolyl) amine (DPA) …

In this contribution, we describe the preparation and recognition characteristics of a novel
tetrapodal benzene cage (1). The cage can express a wide recognition range without losing …

Background Excessive lactate production, a hallmark of cancer, is largely formed by the
reduction of pyruvate via lactate dehydrogenase (LDH) to l-lactate. Although d-lactate can …

The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two
of the most characterized properties of the TME are acidosis and hypoxia, both of which are …

Chiral α‐hydroxyl acids are of great importance in chemical synthesis. Current methods for
recognizing their chirality by 1H NMR are limited by their small chemical shift differences …