RNA structure and cellular applications of fluorescent light‐up aptamers

S Neubacher, S Hennig - Angewandte Chemie International …, 2019 - Wiley Online Library
The cellular functions of RNA are not limited to their role as blueprints for protein synthesis.
In particular, noncoding RNA, such as, snRNAs, lncRNAs, miRNAs, play important roles …

From fluorescent proteins to fluorogenic RNAs: Tools for imaging cellular macromolecules

L Truong, AR Ferré‐D'Amaré - Protein Science, 2019 - Wiley Online Library
The explosion in genome‐wide sequencing has revealed that noncoding RNAs are
ubiquitous and highly conserved in biology. New molecular tools are needed for their study …

Recent development of fluorescent light-up RNA aptamers

H Zhou, S Zhang - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
Technologies for RNA imaging in live cells play an important role in understanding the
function and regulatory process of RNAs. One approach for genetically encoded fluorescent …

Living-cell microRNA imaging with self-assembling fragments of fluorescent protein-mimic RNA aptamer

Y Gu, LJ Huang, W Zhao, TT Zhang, MR Cui… - ACS …, 2021 - ACS Publications
As the cellular roles of RNA abundance continue to increase, there is an urgent need for the
corresponding tools to elucidate native RNA functions and dynamics, especially those of …

Structure–fluorescence activation relationships of a large Stokes shift fluorogenic RNA aptamer

C Steinmetzger, I Bessi, AK Lenz… - Nucleic acids …, 2019 - academic.oup.com
The Chili RNA aptamer is a 52 nt long fluorogen-activating RNA aptamer (FLAP) that confers
fluorescence to structurally diverse derivatives of fluorescent protein chromophores. A key …

Fluorescent platforms for RNA chemical biology research

J Du, R Dartawan, W Rice, F Gao, JH Zhou, J Sheng - Genes, 2022 - mdpi.com
Efficient detection and observation of dynamic RNA changes remain a tremendous
challenge. However, the continuous development of fluorescence applications in recent …

Development and applications of fluorogen/light-up RNA aptamer pairs for RNA detection and more

M Ryckelynck - RNA Tagging: Methods and Protocols, 2020 - Springer
The central role of RNA in living systems made it highly desirable to have noninvasive and
sensitive technologies allowing for imaging the synthesis and the location of these …

[图书][B] Single-stranded RNA phages: From molecular biology to nanotechnology

P Pumpens - 2020 - taylorfrancis.com
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first
discovered in 1961. These phages played a unique role in early studies of molecular …

Fluorescent RNA tags: current and future applications

S Hennig, S Neubacher - Future Medicinal Chemistry, 2019 - Taylor & Francis
The rising interest in the field of RNA research, especially regarding diverse (short and long)
noncoding RNAs, demands for novel techniques to identify, functionally characterize and …

[PDF][PDF] Fluorescent Platforms for RNA Chemical Biology Research. Genes 2022, 13, 1348

J Du, R Dartawan, W Rice, F Gao, JH Zhou, J Sheng - 2022 - academia.edu
Efficient detection and observation of dynamic RNA changes remain a tremendous
challenge. However, the continuous development of fluorescence applications in recent …