Neuropeptides and microglial activation in inflammation, pain, and neurodegenerative diseases

L Carniglia, D Ramírez, D Durand… - Mediators of …, 2017 - Wiley Online Library
Microglial cells are responsible for immune surveillance within the CNS. They respond to
noxious stimuli by releasing inflammatory mediators and mounting an effective inflammatory …

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

W Beumer, SM Gibney, RC Drexhage… - Journal of leukocyte …, 2012 - academic.oup.com
Review on the key role for activated microglia and monocytes in the pathogenesis of bipolar
disorder and schizophrenia. This review describes a key role for mononuclear phagocytes in …

Enduring consequences of maternal obesity for brain inflammation and behavior of offspring

SD Bilbo, V Tsang - The FASEB Journal, 2010 - Wiley Online Library
Obesity is well characterized as a systemic inflammatory condition, and is also associated
with cognitive disruption, suggesting a link between the two. We assessed whether …

Hormones and diet, but not body weight, control hypothalamic microglial activity

Y Gao, N Ottaway, SC Schriever, B Legutko… - Glia, 2014 - Wiley Online Library
The arcuate nucleus (ARC) of the hypothalamus plays a key role in sensing metabolic
feedback and regulating energy homeostasis. Recent studies revealed activation of …

Black Soldier Fly (Hermetia illucens) reared on roasted coffee by-product and Schizochytrium sp. as a sustainable terrestrial ingredient for aquafeeds production

M Zarantoniello, A Zimbelli, B Randazzo… - Aquaculture, 2020 - Elsevier
Promoting circularity in the aquaculture sector through the conversion of great amount of
organic by-products produced on land is a valuable strategy for a further development of the …

Multiple sclerosis and obesity: The role of adipokines

J Correale, M Marrodan - Frontiers in immunology, 2022 - frontiersin.org
Multiple Sclerosis (MS), a chronic inflammatory disease of the central nervous system that
leads to demyelination and neurodegeneration has been associated with various …

Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity

N Castanon, G Luheshi, S Layé - Frontiers in neuroscience, 2015 - frontiersin.org
Obesity is associated with a high prevalence of mood disorders and cognitive dysfunctions
in addition to being a significant risk factor for important health complications such as …

Hypothalamic inflammation in the control of metabolic function

M Valdearcos, AW Xu, SK Koliwad - Annual review of …, 2015 - annualreviews.org
Diet-induced obesity leads to devastating and common chronic diseases, fueling ongoing
interest in determining new mechanisms underlying both obesity and its consequences. It is …

Hypothalamic innate immune reaction in obesity

S Kälin, FL Heppner, I Bechmann, M Prinz… - Nature Reviews …, 2015 - nature.com
Findings from rodent and human studies show that the presence of inflammatory factors is
positively correlated with obesity and the metabolic syndrome. Obesity-associated …

Obesity affects the microbiota–gut–brain axis and the regulation thereof by endocannabinoids and related mediators

N Forte, AC Fernández-Rilo, L Palomba… - International Journal of …, 2020 - mdpi.com
The hypothalamus regulates energy homeostasis by integrating environmental and internal
signals to produce behavioral responses to start or stop eating. Many satiation signals are …