Over the past century, the life expectancy of people born with Down syndrome has
increased from 9 to 60 years, 1 with data indicating that it could match the general …

This meta-analysis, which consisted of a scoping review and retrospective medical record
review, is focused on potential sex differences in cardiovascular diseases in patients with …

Individuals with Down syndrome (DS) are at increased risk for being overweight/obese, but
the associated cardiometabolic risk (CR) is not clear. Cross‐sectional anthropometric and …

Background Obesity is a significant risk factor for Alzheimer's disease; however, this
association has not been explored in adults with Down syndrome. Objective To examine the …

Background—Adults with Down's syndrome (DS) present lower physical fitness associated
with heightened sedentary behaviors and motor skills impairments. Their etiologies and …

Introduction: The genetic disorder causing Down syndrome (DS) affects the
cardiorespiratory and hemodynamic parameters. When exercising, sufficient blood flow is …

Introduction Evidence in the general population suggests that predictors of cardiovascular
health such as moderate to vigorous physical activity (MVPA), cardiorespiratory fitness, and …

This systematic review aimed to provide an overview of test protocols used to measure peak
oxygen uptake (VO2peak) in adults with Down syndrome (DS) and to determine how …

Abstract Background Adults with Down syndrome commonly have low levels of physical
activity and face social barriers to engaging in physical activity, including boredom and …

Individuals with Down syndrome seem to be more likely to have congenital heart disease
(CHD). This situation has led to the need to investigate the effects of exercise and physical …