[HTML][HTML] Exosomal ncRNAs: Multifunctional contributors to the immunosuppressive tumor microenvironment of hepatocellular carcinoma
Q Huang, X Zhong, J Li, R Hu, J Yi, J Sun, Y Xu… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a malignant liver cancer characterized by aggressive
progression, unfavorable prognosis, and an increasing global health burden. Therapies that …
progression, unfavorable prognosis, and an increasing global health burden. Therapies that …
Unraveling Immunological Dynamics: HPV Infection in Women—Insights from Pregnancy
During pregnancy, hormonal and immune adaptations are vital for supporting the genetically
distinct fetus during elevated infection risks. The global prevalence of HPV necessitates its …
distinct fetus during elevated infection risks. The global prevalence of HPV necessitates its …
[HTML][HTML] Metabolic Dysfunction-Associated Steatotic Liver Disease: The Associations between Inflammatory Markers, TLR4, and Cytokines IL-17A/F, and Their …
Background: The pathogenesis of MASLD (metabolic dysfunction-associated steatotic liver
disease) is driven by environmental, genetic, metabolic, immune, and inflammatory factors …
disease) is driven by environmental, genetic, metabolic, immune, and inflammatory factors …
Role of targeting TLR4 signaling axis in liver-related diseases
YL Tang, L Zhu, Y Tao, W Lu, H Cheng - Pathology-Research and Practice, 2023 - Elsevier
Abstract Toll-like receptor 4 (TLR4) plays an important role as a key signal-receiving
transmembrane protein molecule in the liver, and substances that target the liver exert …
transmembrane protein molecule in the liver, and substances that target the liver exert …
The Role of TLR4 in the Immunotherapy of Hepatocellular Carcinoma: Can We Teach an Old Dog New Tricks?
Simple Summary In this study, we investigated the potential of TLR4 to improve the
treatment of hepatocellular carcinoma (HCC). HCC is a serious health concern worldwide …
treatment of hepatocellular carcinoma (HCC). HCC is a serious health concern worldwide …
Regulating Protein–RNA Interactions: Advances in Targeting the LIN28/Let-7 Pathway
Originally discovered in C. elegans, LIN28 is an evolutionarily conserved zinc finger RNA-
binding protein (RBP) that post-transcriptionally regulates genes involved in developmental …
binding protein (RBP) that post-transcriptionally regulates genes involved in developmental …
Exploring the modulation of TLR4 and its associated ncRNAs in cancer immunopathogenesis, with an emphasis on the therapeutic implications and mechanisms …
This study provides an in-depth analysis of the pathogenic relevance, therapeutic
implications, and mechanisms of treatment resistance associated with TLR4 and its ncRNAs …
implications, and mechanisms of treatment resistance associated with TLR4 and its ncRNAs …
Oleander attenuates hepatic inflammation in a TLR4-independent manner and by favorable modulation of hepatocellular global metabolome that supports …
Ethnopharmacological relevance Nerium oleander is used to treat liver-associated chronic
metabolic diseases in traditional medicinal systems across the globe. The hepatoprotective …
metabolic diseases in traditional medicinal systems across the globe. The hepatoprotective …
Epigenetic modification of hepatitis B virus infection and related hepatocellular carcinoma
Y Zhang, W Cao, S Wang, L Zhang, X Li, Z Zhang… - Virulence, 2024 - Taylor & Francis
Hepatitis B virus (HBV) infection poses a challenge to global public health. Persistent liver
infection with HBV is associated with an increased risk of developing severe liver disease …
infection with HBV is associated with an increased risk of developing severe liver disease …
The role of Lin28A and Lin28B in cancer beyond Let‐7
S Cotino‐Nájera, E García‐Villa, S Cruz‐Rosales… - FEBS …, 2024 - Wiley Online Library
Lin28A and Lin28B are paralogous RNA‐binding proteins that play fundamental roles in
development and cancer by regulating the microRNA family of tumor suppressor Let‐7 …
development and cancer by regulating the microRNA family of tumor suppressor Let‐7 …