Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for
Pathogenesis* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement …

The previously established classification (Yarden and Ullrich, 1988) has been extended by
recently described receptor tyrosine kinases such as HER3/c-erbB-3 (Kraus et al., 1989) IRR …

The insulin receptor is a member of the ligand-activated receptor and tyrosine kinase family
of transmembrane signaling proteins that collectively are fundamentally important regulators …

The following brief summary is based on a recent wx review by Rubin and Baserga 1, and
the reader is referred to that review for extended references. A simplified representation of …

The epidermal growth factor receptor plays crucial roles throughout the development of
multicellular organisms, and inappropriate activation of the receptor is associated with …

HER4/ErbB4 is a ubiquitously expressed member of the EGF/ErbB family of receptor
tyrosine kinases that is essential for normal development of the heart, nervous system, and …

Adipocytes have traditionally been considered to be the primary site for whole body energy
storage mainly in the form of triglycerides and fatty acids. This occurs through the ability of …

Interaction of the nerve growth factor (NGF) receptor/Trk with cellular substrates was
investigated by transient co‐overexpression in human 293 fibroblasts using ET‐R, a …

By a frame-shift mutation, we have engineered a human IGF-I receptor (IGF-IR) cDNA that
produces a receptor 486 amino acids long (plus the 30 amino acids of the signal peptide) …

Taz1 is a hybrid signal-transducing membrane receptor between Tar, an aspartate
chemoreceptor, and EnvZ, an osmosensor of Escherichia coli that is able to induce ompC …