Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

Background Clinical prediction models can enhance clinical decision-making and research.
However, available prediction models in aneurysmal subarachnoid hemorrhage (aSAH) are …

Background Receiver operating characteristic (ROC) curves are useful tools to evaluate
classifiers in biomedical and bioinformatics applications. However, conclusions are often …

Handbook of Regression Methods concisely covers numerous traditional, contemporary,
and nonstandard regression methods. The handbook provides a broad overview of …

Background and Purpose—Early prediction of clinical outcome after aneurysmal
subarachnoid hemorrhage (aSAH) is still lacking accuracy. In this observational cohort …

Two-dimensional gel electrophoresis was instrumental in the birth of proteomics in the late
1980s. However, it is now often considered as an outdated technique for proteomics—a …

Diagnostic accuracy can be improved considerably by combining multiple markers, whose
performance in identifying diseased subjects is usually assessed via receiver operating …

Critically ill patients are frequently at risk of neurological dysfunction as a result of primary
neurological conditions or secondary insults. Determining which aspects of brain function …

Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions
detectable using CT scans. However, most patients will be CT-negative. There is thus a …

Background The intracerebral hemorrhage (ICH) score is a simple grading scale that can be
used to stratify risk of 30 day mortality in ICH patients. A similar risk stratification scale for …