Immune modulation by mesenchymal stem cells
W Jiang, J Xu - Cell proliferation, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …
[HTML][HTML] Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application
Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …
nature. Traditional treatment methods are not able to produce satisfactory effects …
Fracture healing: mechanisms and interventions
TA Einhorn, LC Gerstenfeld - Nature Reviews Rheumatology, 2015 - nature.com
Fractures are the most common large-organ, traumatic injuries to humans. The repair of
bone fractures is a postnatal regenerative process that recapitulates many of the ontological …
bone fractures is a postnatal regenerative process that recapitulates many of the ontological …
[HTML][HTML] Immunobiology of mesenchymal stem cells
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively
expanded in vitro. Although their true in situ properties and biological functions remain to be …
expanded in vitro. Although their true in situ properties and biological functions remain to be …
Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications
ME Castro-Manrreza… - Journal of immunology …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …
[HTML][HTML] TNF-α and IFN-γ participate in improving the immunoregulatory capacity of mesenchymal stem/stromal cells: Importance of cell–cell contact and extracellular …
L López-García, ME Castro-Manrreza - International journal of molecular …, 2021 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) have an immunoregulatory capacity and have
been used in different clinical protocols requiring control of the immune response. However …
been used in different clinical protocols requiring control of the immune response. However …
[HTML][HTML] A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype
RS Waterman, SL Tomchuck, SL Henkle… - PloS one, 2010 - journals.plos.org
Background Our laboratory and others reported that the stimulation of specific Toll-like
receptors (TLRs) affects the immune modulating responses of human multipotent …
receptors (TLRs) affects the immune modulating responses of human multipotent …
[HTML][HTML] Mechanisms involved in the therapeutic properties of mesenchymal stem cells
Mesenchymal stem cells (MSCs) have been described as being able to give rise to several
quite different mesenchymal cell phenotypes. However, the ability to differentiate is not the …
quite different mesenchymal cell phenotypes. However, the ability to differentiate is not the …
[HTML][HTML] The critical role of apoptosis in mesenchymal stromal cell therapeutics and implications in homeostasis and normal tissue repair
C Giacomini, C Granéli, R Hicks, F Dazzi - Cellular & Molecular …, 2023 - nature.com
Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …
numerous clinical conditions and have demonstrated good safety but mixed efficacy …
[HTML][HTML] HLA-G: An important mediator of maternal-fetal immune-tolerance
B Zhuang, J Shang, Y Yao - Frontiers in Immunology, 2021 - frontiersin.org
Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a
mother can accept a genetically distinct fetus without immunological aggressive behavior …
mother can accept a genetically distinct fetus without immunological aggressive behavior …