Energy metabolism in ALS: an underappreciated opportunity?
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
Risk factors and emerging therapies in amyotrophic lateral sclerosis
N Nowicka, J Juranek, JK Juranek… - International journal of …, 2019 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease
characterized by a permanent degeneration of both upper and lower motor neurons. Many …
characterized by a permanent degeneration of both upper and lower motor neurons. Many …
Effect of high‐caloric nutrition on survival in amyotrophic lateral sclerosis
AC Ludolph, J Dorst, J Dreyhaupt… - Annals of …, 2020 - Wiley Online Library
Objective Weight loss has been identified as a negative prognostic factor in amyotrophic
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …
Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice
M Wong, LJ Martin - Human molecular genetics, 2010 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of motor neurons
(MNs) that causes skeletal muscle paralysis. Familial forms of ALS are linked to mutations in …
(MNs) that causes skeletal muscle paralysis. Familial forms of ALS are linked to mutations in …
Hypothalamic atrophy is related to body mass index and age at onset in amyotrophic lateral sclerosis
M Gorges, P Vercruysse, HP Müller… - Journal of Neurology …, 2017 - jnnp.bmj.com
Objective Our objective was to study the hypothalamic volume in a cohort of patients with
amyotrophic lateral sclerosis (ALS) including symptomatic and presymptomatic ALS …
amyotrophic lateral sclerosis (ALS) including symptomatic and presymptomatic ALS …
Metabolic abnormalities, dietary risk factors and nutritional management in amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative
disease that affects motor neurons, leading to a relentless paralysis of skeletal muscles and …
disease that affects motor neurons, leading to a relentless paralysis of skeletal muscles and …
Amyotrophic lateral sclerosis and frontotemporal dementia: distinct and overlapping changes in eating behaviour and metabolism
Metabolic changes incorporating fluctuations in weight, insulin resistance, and cholesterol
concentrations have been identified in several neurodegenerative disorders. Whether these …
concentrations have been identified in several neurodegenerative disorders. Whether these …
Diet, microbiota and brain health: unraveling the network intersecting metabolism and neurodegeneration
F Gentile, PE Doneddu, N Riva… - International journal of …, 2020 - mdpi.com
Increasing evidence gives support for the idea that extra-neuronal factors may affect brain
physiology and its predisposition to neurodegenerative diseases. Epidemiological and …
physiology and its predisposition to neurodegenerative diseases. Epidemiological and …
[HTML][HTML] A plural role for lipids in motor neuron diseases: energy, signaling and structure
Motor neuron diseases (MNDs) are characterized by selective death of motor neurons and
include mainly adult-onset amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy …
include mainly adult-onset amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy …
Nutritional and metabolic factors in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …
classically thought to impact the motor system. Over the past 20 years, research has started …