Risk factors and biomarkers of age-related macular degeneration

NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

Smoking and age‐related macular degeneration: review and update

S Velilla, JJ García-Medina… - Journal of …, 2013 - Wiley Online Library
Age‐related macular degeneration (AMD) is one of the main socioeconomical health issues
worldwide. AMD has a multifactorial etiology with a variety of risk factors. Smoking is the …

The diagnostic yield of next generation sequencing in inherited retinal diseases: a systematic review and meta-analysis

AC Britten-Jones, SA Gocuk, KL Goh, A Huq… - American Journal of …, 2023 - Elsevier
PURPOSE Accurate genotyping of individuals with inherited retinal diseases (IRD) is
essential for patient management and identifying suitable candidates for gene therapies …

[HTML][HTML] Nonsyndromic retinitis pigmentosa overview

AT Fahim, SP Daiger, RG Weleber - GeneReviews®[Internet], 2023 - ncbi.nlm.nih.gov
Retinitis pigmentosa (RP) refers to a group of inherited disorders in which abnormalities of
the photoreceptors (rods and cones) of the retina lead to progressive visual loss. RP is …

Gene therapy for RPE65-related retinal disease

V Miraldi Utz, RG Coussa, F Antaki… - Ophthalmic …, 2018 - Taylor & Francis
Significant discoveries in the etiology and pathogenesis of inherited retinal diseases (IRDs)
have been made in the last few decades. Of the large number genes that cause IRDs, bi …

Pediatric eye evaluations preferred practice pattern®: I. Vision screening in the primary care and community setting; II. Comprehensive ophthalmic examination

DK Wallace, CL Morse, M Melia, DT Sprunger… - …, 2018 - aaojournal.org
Vision screening for children is an evaluation to detect reduced visual acuity or risk factors
that threaten the healthy growth and development of the eye and visual system. Vision …

Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine

ME Fini, SG Schwartz, X Gao, S Jeong, N Patel… - Progress in retinal and …, 2017 - Elsevier
Elevation of intraocular pressure (IOP) due to therapeutic use of glucocorticoids is called
steroid-induced ocular hypertension (SIOH); this can lead to steroid-induced glaucoma …

Genetic testing and diagnosis of inherited retinal diseases

BL Lam, BP Leroy, G Black, T Ong, D Yoon… - Orphanet journal of rare …, 2021 - Springer
Inherited retinal diseases (IRDs) are a diverse group of degenerative diseases of the retina
that can lead to significant reduction in vision and blindness. Because of the considerable …

Pediatric eye evaluations preferred practice pattern

AK Hutchinson, CL Morse, A Hercinovic… - …, 2022 - pmc.ncbi.nlm.nih.gov
Vision screening for children is an evaluation to detect reduced visual acuity or risk factors
that threaten the healthy growth and development of the eye and visual system. Vision …

Familial normal tension glaucoma genetics

AR Fox, JH Fingert - Progress in retinal and eye research, 2023 - Elsevier
Glaucoma is defined by characteristic optic nerve damage and corresponding visual field
defects and is the leading cause of irreversible blindness in the world. Elevated intraocular …