Targeting DNA topoisomerase II in antifungal chemotherapy

K Kondaka, I Gabriel - Molecules, 2022 - mdpi.com
Topoisomerase inhibitors have been in use clinically for the treatment of several diseases
for decades. Although those enzymes are significant molecular targets in antibacterial and …

[HTML][HTML] Review and Current Perspectives on DNA Topoisomerase I and II Enzymes of Fungi as Study Models for the Development of New Antifungal Drugs

D Andrade-Pavón, O Gómez-García, L Villa-Tanaca - Journal of Fungi, 2024 - mdpi.com
Fungal infections represent a growing public health problem, mainly stemming from two
phenomena. Firstly, certain diseases (eg, AIDS and COVID-19) have emerged that weaken …

Targeting DNA Topoisomerase II in Antifungal Chemotherapy

K Kondaka, I Gabriel - Molecules - europepmc.org
Topoisomerase inhibitors have been in use clinically for the treatment of several diseases
for decades. Although those enzymes are significant molecular targets in antibacterial and …