Congenital human cytomegalovirus (HCMV) is the most common viral infection of the
developing fetus, and a significant cause of neurodevelopmental abnormalities in infants …

Vaccination is arguably the most cost-effective preventative measure against infectious
diseases. While vaccines have been successfully developed against certain viruses (eg …

Human cytomegalovirus (HCMV) is a highly prevalent herpesvirus that can cause severe
disease in immunocompromised individuals and immunologically immature fetuses and …

Cytomegaloviruses (CMVs) are highly prevalent, persistent human pathogens that not only
evade but also shape our immune responses. Natural killer (NK) cells play an important role …

Typically, during viral infections, T cells encounter antigen, undergo proliferative expansion
and ultimately contract into a pool of memory cells. However, after infection with …

Infections in early life can elicit substantially different immune responses and pathogenesis
than infections in adulthood. Here, we investigate the consequences of murine …

Natural killer (NK) cells play an important role in the host response against viral infections
and cancer development. They are able to kill virus-infected and tumor cells, and they …

Increased evidence of cross-talk between NK cells and other immune cells has enhanced
the possibilities of exploiting the interplay between the activation and inhibition of NK cells …

Coordination of the innate and adaptive immune systems is paramount to the development
of protective humoral and cellular immunity following vaccination. Natural killer (NK) cells …

Natural killer (NK) cells and CD8+ T cells play a prominent role in the clearance of mouse
cytomegalovirus (MCMV) infection. The role of NK cells in modulating the CD8+ T-cell …