The muscular dystrophies are rare orphan diseases, characterized by progressive muscle
weakness: the most common and well known is Duchenne muscular dystrophy which affects …

Recent years have seen tremendous progress towards therapy of many previously incurable
neuromuscular diseases. This new context has acted as a driving force for the development …

Background A substantial impediment to progress in trials of new therapies in
neuromuscular disorders is the absence of responsive outcome measures that correlate with …

Clinical, laboratory and electrodiagnostic studies are the mainstay in the diagnosis of
polyneuropathy. An accurate etiological diagnosis is of paramount importance to provide the …

Neuromuscular diseases are characterized by progressive muscle degeneration and
muscle weakness resulting in functional disabilities. While each of these diseases is …

Study Design. A population based cross-sectional study. Objective. To clarify relative
constituents of viable muscle in 2-dimensional cross-sectional area (CSA) measures of …

Idiopathic inflammatory myopathies (IIMs) are a group of acquired muscle diseases with
muscle inflammation, weakness, and other extra-muscular manifestations. IIMs can …

Background and Objectives Limited data suggest that quantitative MRI (qMRI) measures
have potential to be used as trial outcome measures in sporadic inclusion body myositis …

The progressive replacement of muscle tissue by fat in Duchenne muscular dystrophy
(DMD) has been studied using quantitative MRI between, but not within, individual muscles …

High resolution and high field magnetic resonance neurography (MR neurography, MRN) is
shown to have excellent anatomic capability. There have been considerable advances in …