Background Preliminary evaluations of behavioral interventions, referred to as pilot studies,
predate the conduct of many large-scale efficacy/effectiveness trial. The ability of a pilot …

Importance Spin, the inaccurate reporting of randomized clinical trials (RCTs) with results
that are not statistically significant for the primary end point, distorts interpretation of results …

In an era of evidence-based medicine, peer review is an engine and protector of that
evidence. Such evidence, vetted by and surviving the peer review process, serves to inform …

The lack of research reproducibility has caused growing concern across various scientific
fields [1–5]. Today, there is widespread agreement, within and outside academia, that …

Purpose “Spin,” a slang term meaning the misrepresentation of study findings such that the
beneficial effects of an intervention are magnified beyond what the results actually show, is a …

Background Given variable frequency of misleading reports and the potential for spin (a way
of describing results that can mislead readers) to influence interpretation of randomised …

Objectives To identify the presence and characteristics of spin (using reporting strategies to
distort study results and mislead readers) within randomized controlled trial (RCT) abstracts …

The power of language to modify the reader's perception of interpreting biomedical results
cannot be underestimated. Misreporting and misinterpretation are pressing problems in …

EditordAlthough perioperative physicians continue to debate propositions and oppositions
to evidence-based practice in anaesthesia, the need for reflection upon the objectivity and …

Evidence-based medicine is the cornerstone of shared-decision making in healthcare today.
The public deserves clear, transparent and trust-worthy information on drug efficacy. Yet …