Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

[HTML][HTML] Nanotheranostics˗ application and further development of nanomedicine strategies for advanced theranostics

MS Muthu, DT Leong, L Mei, SS Feng - Theranostics, 2014 - ncbi.nlm.nih.gov
Nanotheranostics is to apply and further develop nanomedicine strategies for advanced
theranostics. This review summarizes the various nanocarriers developed so far in the …

Imaging and drug delivery using theranostic nanoparticles

SM Janib, AS Moses, JA MacKay - Advanced drug delivery reviews, 2010 - Elsevier
Nanoparticle technologies are significantly impacting the development of both therapeutic
and diagnostic agents. At the intersection between treatment and diagnosis, interest has …

Improving kidney targeting: The influence of nanoparticle physicochemical properties on kidney interactions

Y Huang, J Wang, K Jiang, EJ Chung - Journal of Controlled Release, 2021 - Elsevier
Kidney-targeted nanoparticles have become of recent interest due to their potential to
deliver drugs directly to diseased tissue, decrease off-target adverse effects, and increase …

Nanomedicines for renal disease: current status and future applications

N Kamaly, JC He, DA Ausiello… - Nature Reviews …, 2016 - nature.com
Abstract Treatment and management of kidney disease currently presents an enormous
global burden, and the application of nanotechnology principles to renal disease therapy …

Nanotechnology applied to overcome tumor drug resistance

Z Gao, L Zhang, Y Sun - Journal of controlled release, 2012 - Elsevier
Emerging multidrug resistance (MDR) to chemotherapy is a major obstacle in successfully
treating malignant diseases. Nanotechnology provides an innovative and promising …

Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers

T Lammers, V Subr, K Ulbrich, P Peschke, PE Huber… - Biomaterials, 2009 - Elsevier
Copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) are prototypic and well-
characterized polymeric drug carriers that have been broadly implemented in the delivery of …

Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment

A David - Advanced drug delivery reviews, 2017 - Elsevier
Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …

Drug targeting to the kidney: Advances in the active targeting of therapeutics to proximal tubular cells

MEM Dolman, S Harmsen, G Storm… - Advanced drug delivery …, 2010 - Elsevier
Activated signaling cascades in the proximal tubular cells of the kidneys play a crucial role in
the development of tubulointerstitial fibrosis. Inhibition of these signaling cascades with …

Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy

T Lammers, V Subr, K Ulbrich, WE Hennink, G Storm… - Nano Today, 2010 - Elsevier
Nanomedicine systems aim to improve the biodistribution and the target site accumulation of
systemically applied (chemo-) therapeutics. By increasing drug localization at the …