Irritable bowel syndrome: towards biomarker identification

G Clarke, EMM Quigley, JF Cryan, TG Dinan - Trends in molecular …, 2009 - cell.com
Irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder
referred to gastroenterologists, affects 7–10% of the general population worldwide. The lack …

Pain management in patients with inflammatory bowel disease: insights for the clinician

AI Srinath, C Walter, MC Newara… - Therapeutic …, 2012 - journals.sagepub.com
Abdominal pain is a common symptom in patients with inflammatory bowel disease (IBD)
and has a profound negative impact on patients' lives. There are growing data suggesting …

Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome

G Le Gall, SO Noor, K Ridgway, L Scovell… - Journal of proteome …, 2011 - ACS Publications
1H NMR spectroscopy of aqueous fecal extracts has been used to investigate differences in
metabolic activity of gut microbiota in patients with ulcerative colitis (UC)(n= 13), irritable …

[HTML][HTML] Irritable bowel syndrome: diagnosis and pathogenesis

M El-Salhy - World journal of gastroenterology: WJG, 2012 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) disorder that considerably
reduces the quality of life. It further represents an economic burden on society due to the …

Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota

SO Noor, K Ridgway, L Scovell, EK Kemsley… - BMC …, 2010 - Springer
Background Previous studies suggest a link between gut microbiota and the development of
ulcerative colitis (UC) and irritable bowel syndrome (IBS). Our aim was to investigate any …

[HTML][HTML] Regulation of the serotonin transporter in the pathogenesis of irritable bowel syndrome

DC Jin, HL Cao, MQ Xu, SN Wang… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Abstract Serotonin (5-HT) and the serotonin transporter (SERT) have earned a tremendous
amount of attention regarding the pathogenesis of irritable bowel syndrome (IBS) …

Resistance to early-life stress in mice: effects of genetic background and stress duration

HM Savignac, TG Dinan, JF Cryan - Frontiers in behavioral …, 2011 - frontiersin.org
Early-life stress can induce marked behavioral and physiological impairments in adulthood
including cognitive deficits, depression, anxiety, and gastrointestinal dysfunction. Although …

Pain/depression dyad: a key to a better understanding and treatment of functional somatic syndromes

DL Goldenberg - The American journal of medicine, 2010 - Elsevier
Functional somatic syndromes include some of the most common and frustrating illnesses
seen by primary care physicians and medical specialists. An extensive literature search of …

Current insights in to the pathophysiology of irritable bowel syndrome

T Karantanos, T Markoutsaki, M Gazouli, NP Anagnou… - Gut Pathogens, 2010 - Springer
Abstract Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal
tract without the presence of an anatomic defect, in which abdominal pain is relieved with …

[HTML][HTML] Is irritable bowel syndrome an organic disorder?

M El-Salhy, D Gundersen, OH Gilja… - World journal of …, 2014 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is generally
considered to be functional because there appears to be no associated anatomical defect …