Polyglutamine disorders: Pathogenesis and potential drug interventions

S Tandon, P Aggarwal, S Sarkar - Life Sciences, 2024 - Elsevier
Polyglutamine/poly (Q) diseases are a group nine hereditary neurodegenerative disorders
caused due to abnormally expanded stretches of CAG trinucleotide in functionally distinct …

Coenzyme Q10: Role in less common age-related disorders

D Mantle, IP Hargreaves - Antioxidants, 2022 - mdpi.com
In this article we have reviewed the potential role of coenzyme Q10 (CoQ10) in the
pathogenesis and treatment of a number of less common age-related disorders, for many of …

Ubiquinol preserves immune cells in gamma-irradiated rats: Role of autophagy and apoptosis in splenic tissue

NM Elkenawy, HR Ghaiad, SM Ibrahim, RK Aziz… - International …, 2023 - Elsevier
Radiation has been applied in cancer treatment to eradicate tumors and displayed great
therapeutic benefits for humans. However, it is associated with negative impacts on normal …

A pilot study: handgrip as a predictor in the disease progression of SCA3

C Chiu, W Cheng, Y Lin, T Lin, H Chang… - Orphanet Journal of …, 2023 - Springer
Background Spinocerebellar ataxia type 3 (SCA3) is an inherited, autosomal, and rare
neurodegenerative disease. Serum/plasma biomarkers or functional magnetic resonance …

Hereditary Ataxias: From Bench to Clinic, Where Do We Stand?

F Pilotto, A Del Bondio, H Puccio - Cells, 2024 - mdpi.com
Cerebellar ataxias are a wide heterogeneous group of movement disorders. Within this
broad umbrella of diseases, there are both genetics and sporadic forms. The clinical …

Ataksje rdzeniowo-móżdżkowe w Polsce

J Dulski, A Sułek, J Sławek… - Polski Przegląd …, 2023 - journals.viamedica.pl
Ataksja (niezborność ruchowa, bezład) jest zespołem objawów charakteryzującym się
zaburzeniami równowagi i koordynacji chodu, postawy, ruchów kończyn oraz …

New Biomarker in Spinocerebellar ataxia type 3: Handgrip Strength

CM Chiu, WL Cheng, YS Lin, TT Lin, HJ Chang… - 2023 - researchsquare.com
Background Spinocerebellar ataxia type 3 (SCA3) is an inherited, autosomal, and rare
neurodegenerative disease. Serum/plasma biomarkers or functional magnetic resonance …

[PDF][PDF] AUTOMATION OF BEHAVIOURAL TESTS ON ANIMAL MODELS OF MACHADO JOSEPH'S

LCPP Angeja - 2023 - estudogeral.uc.pt
Machado Joseph disease (MJD) or Spinocerebellar Ataxia Type 3 (SCA3) is a
neurodegenerative disorder characterised by an expansion of a CAG repeat in the coding …