Developments and applications of functional protein microarrays

GD Syu, J Dunn, H Zhu - Molecular & Cellular Proteomics, 2020 - ASBMB
Protein microarrays are crucial tools in the study of proteins in an unbiased, high-throughput
manner, as they allow for characterization of up to thousands of individually purified proteins …

Anti-cancer auto-antibodies: Roles, applications and open issues

H de Jonge, L Iamele, M Maggi, G Pessino, C Scotti - Cancers, 2021 - mdpi.com
Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …

Non-animal models in dermatological research

E Dellambra, T Odorisio, D D'Arcangelo… - ALTEX-Alternatives to …, 2019 - altex.org
Despite being widely used for basic and preclinical studies in dermatology, available animal
models only partly recapitulate human skin features, often leading to disappointing outputs …

A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors

A Halder, D Biswas, A Chauhan, A Saha… - Clinical Proteomics, 2023 - Springer
Background Meningiomas are the most prevalent primary brain tumors. Due to their
increasing burden on healthcare, meningiomas have become a pivot of translational …

A protein microarray‐based serum proteomic investigation reveals distinct autoantibody signature in colorectal cancer

A Barpanda, C Tuckley, A Ray… - PROTEOMICS …, 2023 - Wiley Online Library
Purpose Colorectal cancer (CRC) has been reported as the second leading cause of cancer
death worldwide. The 5‐year annual survival is around 50%, mainly due to late diagnosis …

Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis

M Garranzo-Asensio, P San Segundo-Acosta… - Journal of …, 2020 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer related death worldwide. Its diagnosis at early stages would significantly improve the …

Emerging role of T3-binding protein μ-crystallin (CRYM) in health and disease

O Aksoy, B Hantusch, L Kenner - Trends in Endocrinology & Metabolism, 2022 - cell.com
Thyroid hormones are essential metabolic and developmental regulators that exert a huge
variety of effects in different organs. Triiodothyronine (T3) and thyroxine (T4) are synthesized …

Evaluation of autoantibody signatures in pituitary adenoma patients using human proteome arrays

A Banerjee, A Ray, A Barpanda, A Dash… - PROTEOMICS …, 2022 - Wiley Online Library
Purpose To identify the specific diagnostic biomarkers related to pituitary adenomas (PAs),
we performed serological antibody profiles for three types of PAs, namely Acromegaly …

Proteome microarray technology and application: higher, wider, and deeper

H Qi, F Wang, S Tao - Expert Review of Proteomics, 2019 - Taylor & Francis
Introduction: Protein microarray is a powerful tool for both biological study and clinical
research. The most useful features of protein microarrays are their miniaturized size (low …

Bone invasive meningioma: recent advances and therapeutic perspectives

H Takase, T Yamamoto - Frontiers in Oncology, 2022 - frontiersin.org
Meningioma is the most common primary neoplasm of the central nervous system (CNS).
Generally, these tumors are benign and have a good prognosis. However, treatment can be …