Structure, function, and pharmacology of glutamate receptor ion channels

KB Hansen, LP Wollmuth, D Bowie, H Furukawa… - Pharmacological …, 2021 - ASPET
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

The Hierarchical Taxonomy of Psychopathology (HiTOP): A quantitative nosology based on consensus of evidence

R Kotov, RF Krueger, D Watson… - Annual review of …, 2021 - annualreviews.org
Traditional diagnostic systems went beyond empirical evidence on the structure of mental
health. Consequently, these diagnoses do not depict psychopathology accurately, and their …

The C Factor: Cognitive dysfunction as a transdiagnostic dimension in psychopathology

A Abramovitch, T Short, A Schweiger - Clinical Psychology Review, 2021 - Elsevier
Research into cognitive functions across psychological disorders suggests that cognitive
deficiencies may be present across multiple disorders, potentially pointing to a …

[PDF][PDF] Functional neuroimaging in psychiatry and the case for failing better

MM Nour, Y Liu, RJ Dolan - Neuron, 2022 - cell.com
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …

[HTML][HTML] A review of heterogeneity in attention deficit/hyperactivity disorder (ADHD)

Y Luo, D Weibman, JM Halperin, X Li - Frontiers in human …, 2019 - frontiersin.org
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects
approximately 8%-12% of children worldwide. Throughout an individual's lifetime, ADHD …

[HTML][HTML] Genetic testing in neurodevelopmental disorders

JM Savatt, SM Myers - Frontiers in Pediatrics, 2021 - frontiersin.org
Neurodevelopmental disorders are the most prevalent chronic medical conditions
encountered in pediatric primary care. In addition to identifying appropriate descriptive …

Annual Research Review: Suicide among youth–epidemiology,(potential) etiology, and treatment

CB Cha, PJ Franz, E M. Guzmán… - Journal of Child …, 2018 - Wiley Online Library
Background Suicide is a leading cause of death and a complex clinical outcome. Here, we
summarize the current state of research pertaining to suicidal thoughts and behaviors in …

Dimensions over categories: A meta-analysis of taxometric research

N Haslam, MJ McGrath, W Viechtbauer… - Psychological …, 2020 - cambridge.org
Taxometric procedures have been used extensively to investigate whether individual
differences in personality and psychopathology are latently dimensional or categorical …

Uncovering the structure of self-regulation through data-driven ontology discovery

IW Eisenberg, PG Bissett, A Zeynep Enkavi, J Li… - Nature …, 2019 - nature.com
Psychological sciences have identified a wealth of cognitive processes and behavioral
phenomena, yet struggle to produce cumulative knowledge. Progress is hamstrung by …

Mental health in UK Biobank–development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis

KAS Davis, JRI Coleman, M Adams, N Allen… - BJPsych …, 2020 - cambridge.org
BackgroundUK Biobank is a well-characterised cohort of over 500 000 participants including
genetics, environmental data and imaging. An online mental health questionnaire was …