[HTML][HTML] Advancements in nanoparticle-based treatment approaches for skin cancer therapy
Skin cancer has emerged as the fifth most commonly reported cancer in the world, causing a
burden on global health and the economy. The enormously rising environmental changes …
burden on global health and the economy. The enormously rising environmental changes …
[HTML][HTML] Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges
MDA Paskeh, F Ghadyani, M Hashemi… - Pharmacological …, 2023 - Elsevier
Cancer progression results from activation of various signaling networks. Among these,
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy
M Hashemi, MS Moosavi, HM Abed, M Dehghani… - Pharmacological …, 2022 - Elsevier
Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …
epigenetic level can be considered as important drivers. Epigenetic factors include a large …
Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …
Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response
M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
[HTML][HTML] Bioaccessibility and bioavailability of diet polyphenols and their modulation of gut microbiota
T Lippolis, M Cofano, GR Caponio… - International Journal of …, 2023 - mdpi.com
It is generally accepted that diet-derived polyphenols are bioactive compounds with several
potentially beneficial effects on human health. In general, polyphenols have several …
potentially beneficial effects on human health. In general, polyphenols have several …
[HTML][HTML] Interplay of dietary antioxidants and gut microbiome in human health: What has been learnt thus far?
The human gastrointestinal tract harbors a diverse range of microbial species, which helps
to regulate various biological processes such as homeostasis of the gut barrier, stimulation …
to regulate various biological processes such as homeostasis of the gut barrier, stimulation …
[HTML][HTML] The Warburg effect: a score for many instruments in the concert of cancer and cancer niche cells
M Jaworska, J Szczudło, A Pietrzyk, J Shah… - Pharmacological …, 2023 - Springer
Although Warburg's discovery of intensive glucose uptake by tumors, followed by lactate
fermentation in oxygen presence of oxygen was made a century ago, it is still an area of …
fermentation in oxygen presence of oxygen was made a century ago, it is still an area of …
Effects and mechanisms of resveratrol for prevention and management of cancers: An updated review
SX Wu, RG Xiong, SY Huang, DD Zhou… - Critical Reviews in …, 2023 - Taylor & Francis
Cancer is a severe public health problem. Resveratrol is a famous natural compound that
has various bioactivities, such as antioxidant, anti-inflammatory, antidiabetic and antiaging …
has various bioactivities, such as antioxidant, anti-inflammatory, antidiabetic and antiaging …
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …
ROS are typically produced under physiological conditions and play crucial roles in living …