[HTML][HTML] Advancements in nanoparticle-based treatment approaches for skin cancer therapy

L Zeng, BHJ Gowda, MG Ahmed, MAS Abourehab… - Molecular Cancer, 2023 - Springer
Skin cancer has emerged as the fifth most commonly reported cancer in the world, causing a
burden on global health and the economy. The enormously rising environmental changes …

[HTML][HTML] Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges

MDA Paskeh, F Ghadyani, M Hashemi… - Pharmacological …, 2023 - Elsevier
Cancer progression results from activation of various signaling networks. Among these,
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …

Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy

M Hashemi, MS Moosavi, HM Abed, M Dehghani… - Pharmacological …, 2022 - Elsevier
Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer

S Mirzaei, MH Gholami, A Zabolian, H Saleki… - Pharmacological …, 2021 - Elsevier
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

[HTML][HTML] Bioaccessibility and bioavailability of diet polyphenols and their modulation of gut microbiota

T Lippolis, M Cofano, GR Caponio… - International Journal of …, 2023 - mdpi.com
It is generally accepted that diet-derived polyphenols are bioactive compounds with several
potentially beneficial effects on human health. In general, polyphenols have several …

[HTML][HTML] Interplay of dietary antioxidants and gut microbiome in human health: What has been learnt thus far?

N Naliyadhara, A Kumar, SK Gangwar… - Journal of Functional …, 2023 - Elsevier
The human gastrointestinal tract harbors a diverse range of microbial species, which helps
to regulate various biological processes such as homeostasis of the gut barrier, stimulation …

[HTML][HTML] The Warburg effect: a score for many instruments in the concert of cancer and cancer niche cells

M Jaworska, J Szczudło, A Pietrzyk, J Shah… - Pharmacological …, 2023 - Springer
Although Warburg's discovery of intensive glucose uptake by tumors, followed by lactate
fermentation in oxygen presence of oxygen was made a century ago, it is still an area of …

Effects and mechanisms of resveratrol for prevention and management of cancers: An updated review

SX Wu, RG Xiong, SY Huang, DD Zhou… - Critical Reviews in …, 2023 - Taylor & Francis
Cancer is a severe public health problem. Resveratrol is a famous natural compound that
has various bioactivities, such as antioxidant, anti-inflammatory, antidiabetic and antiaging …

Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis

HS Tuli, J Kaur, K Vashishth, K Sak, U Sharma… - Archives of …, 2023 - Springer
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …