Measurably evolving pathogens in the genomic era
Current sequencing technologies have created unprecedented opportunities for studying
microbial populations. For pathogens with comparatively low per-site mutation rates, such as …
microbial populations. For pathogens with comparatively low per-site mutation rates, such as …
Confirmed and Potential Sources of Legionella Reviewed
E Van Heijnsbergen, JAC Schalk… - … science & technology, 2015 - ACS Publications
Legionella bacteria are ubiquitous in natural matrices and man-made systems. However, it
is not always clear if these reservoirs can act as source of infection resulting in cases of …
is not always clear if these reservoirs can act as source of infection resulting in cases of …
More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells
L Gomez-Valero, C Rusniok… - Proceedings of the …, 2019 - National Acad Sciences
The genus Legionella comprises 65 species, among which Legionella pneumophila is a
human pathogen causing severe pneumonia. To understand the evolution of an …
human pathogen causing severe pneumonia. To understand the evolution of an …
SNVPhyl: a single nucleotide variant phylogenomics pipeline for microbial genomic epidemiology
The recent widespread application of whole-genome sequencing (WGS) for microbial
disease investigations has spurred the development of new bioinformatics tools, including a …
disease investigations has spurred the development of new bioinformatics tools, including a …
[HTML][HTML] Quantifying the transmission of antimicrobial resistance at the human and livestock interface with genomics
Background Livestock have been implicated as a reservoir for antimicrobial resistance
(AMR) that can spread to humans. Close proximity and ecological interfaces involving …
(AMR) that can spread to humans. Close proximity and ecological interfaces involving …
Evolutionary Processes in the Emergence and Recent Spread of the Syphilis Agent, Treponema pallidum
The incidence of syphilis has risen worldwide in the last decade in spite of being an easily
treated infection. The causative agent of this sexually transmitted disease is the bacterium …
treated infection. The causative agent of this sexually transmitted disease is the bacterium …
Inferences from tip‐calibrated phylogenies: a review and a practical guide
Molecular dating of phylogenetic trees is a growing discipline using sequence data to co‐
estimate the timing of evolutionary events and rates of molecular evolution. All molecular …
estimate the timing of evolutionary events and rates of molecular evolution. All molecular …
Amoebae as training grounds for microbial pathogens
Grazing of amoebae on microorganisms represents one of the oldest predator-prey dynamic
relationships in nature. It represents a genetic “melting pot” for an ancient and continuous …
relationships in nature. It represents a genetic “melting pot” for an ancient and continuous …
Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently
S David, C Rusniok, M Mentasti… - Genome …, 2016 - genome.cshlp.org
Legionella pneumophila is an environmental bacterium and the leading cause of
Legionnaires' disease. Just five sequence types (ST), from more than 2000 currently …
Legionnaires' disease. Just five sequence types (ST), from more than 2000 currently …
Insights on the Emergence of Mycobacterium tuberculosis from the Analysis of Mycobacterium kansasii
J Wang, F McIntosh, N Radomski… - Genome biology and …, 2015 - academic.oup.com
By phylogenetic analysis, Mycobacterium kansasii is closely related to Mycobacterium
tuberculosis. Yet, although both organisms cause pulmonary disease, M. tuberculosis is a …
tuberculosis. Yet, although both organisms cause pulmonary disease, M. tuberculosis is a …