Natural inhibitors of cholinesterases: chemistry, structure–activity and methods of their analysis
N Smyrska-Wieleba, T Mroczek - International Journal of Molecular …, 2023 - mdpi.com
This article aims to provide an updated description and comparison of the data currently
available in the literature (from the last 15 years) on the studied natural inhibitors of …
available in the literature (from the last 15 years) on the studied natural inhibitors of …
Hypoxia-Induced Neuroinflammation in Alzheimer's Disease: Potential Neuroprotective Effects of Centella asiatica
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterised by the
presence of extracellular beta-amyloid fibrillary plaques and intraneuronal neurofibrillary tau …
presence of extracellular beta-amyloid fibrillary plaques and intraneuronal neurofibrillary tau …
Development and Optimization of Nanoemulsion from Ethanolic Extract of Centella asiatica (NanoSECA) Using D‐Optimal Mixture Design to Improve Blood‐Brain …
The evidence on the neuroprotective impact of Centella asiatica (C. asiatica) has been
greatly documented in recent years. However, a major obstacle that remains to be overcome …
greatly documented in recent years. However, a major obstacle that remains to be overcome …
Lactic acid bacteria (LAB) and neuroprotection, what is new? An up-to-date systematic review
Background: In recent years, the potential role of probiotics has become prominent in the
discoveries of neurotherapy against neurodegenerative diseases, such as Alzheimer's and …
discoveries of neurotherapy against neurodegenerative diseases, such as Alzheimer's and …
In vitro cytotoxicity assay, mushroom tyrosinase inhibitory activity and release analysis of kojic monooleate nanodelivery system and in silico molecular docking study …
Tyrosinase is the main enzyme that catalyzes the browning of fruits, fungi and vegetables,
and melanogenesis process in mammals. Kojic monooleate (KMO) is an ester produced via …
and melanogenesis process in mammals. Kojic monooleate (KMO) is an ester produced via …
The standardized extract of Centella asiatica and its fractions exert antioxidative and anti-neuroinflammatory effects on microglial cells and regulate the Nrf2/HO-1 …
A Hambali, NA Jusril, NF Md Hashim… - Journal of …, 2024 - content.iospress.com
Background: Neuroinflammation and oxidative stress can aggravate the progression of
Alzheimer's disease (AD). Centella asiatica has been traditionally consumed for memory …
Alzheimer's disease (AD). Centella asiatica has been traditionally consumed for memory …
[HTML][HTML] A novel glutathione-S-transferase-based biosensor for pyrethroid insecticides: From inhibition study to detection
In this study, the inhibitory potential of four pyrethroid compounds on glutathione S-
transferase (GST) by using molecular docking and in vitro assays was evaluated. Docking …
transferase (GST) by using molecular docking and in vitro assays was evaluated. Docking …
Molecular and Pharmacokinetic Aspects of the Acetylcholinesterase-Inhibitory Potential of the Oleanane-Type Triterpenes and Their Glycosides
K Stępnik, W Kukula-Koch, W Płaziński - Biomolecules, 2023 - mdpi.com
The acetylcholinesterase-inhibitory potential of the oleanane-type triterpenes and their
glycosides from thebark of Terminalia arjuna (Combreatceae), ie, arjunic acid, arjunolic acid …
glycosides from thebark of Terminalia arjuna (Combreatceae), ie, arjunic acid, arjunolic acid …
Centella asiatica improves memory and executive function in middle-aged rats by controlling oxidative stress and cholinergic transmission
Ethnopharmacological relevance Centella asiatica (L.) Urban, is a medicinal herb with rich
history of traditional use in Indian subcontinent. This herb has been valued for its diverse …
history of traditional use in Indian subcontinent. This herb has been valued for its diverse …
Identifying Potential Human Monoacylglycerol Lipase Inhibitors from the Phytoconstituents of Morinda Citrifolia L. Fruits by in silico Pharmacology and in vitro Study
Background Human monoacylglycerol lipase (MGL) is accountable for the hydrolysis of 2-
arachidonoylglycerol (2-AG), thus contributing pivotally to neuroprotection because 2-AG is …
arachidonoylglycerol (2-AG), thus contributing pivotally to neuroprotection because 2-AG is …