Lyme borreliosis

AC Steere, F Strle, GP Wormser, LT Hu… - Nature reviews Disease …, 2016 - nature.com
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of
the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in …

Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Lyme disease pathogenesis

J Coburn, B Garcia, LT Hu, MW Jewett… - Current issues in …, 2021 - mdpi.com
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

JD Radolf, MJ Caimano, B Stevenson… - Nature reviews …, 2012 - nature.com
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen

JD Radolf, RK Deka, A Anand, D Šmajs… - Nature Reviews …, 2016 - nature.com
The past two decades have seen a worldwide resurgence in infections caused by
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …

Bacterial stress responses as potential targets in overcoming antibiotic resistance

J Dawan, J Ahn - Microorganisms, 2022 - mdpi.com
Bacteria can be adapted to adverse and detrimental conditions that induce general and
specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative …

Diagnosis of Lyme borreliosis

ME Aguero-Rosenfeld, G Wang… - Clinical microbiology …, 2005 - Am Soc Microbiol
SUMMARY A large amount of knowledge has been acquired since the original descriptions
of Lyme borreliosis (LB) and of its causative agent, Borrelia burgdorferi sensu stricto. The …

Biology of infection with Borrelia burgdorferi

K Tilly, PA Rosa, PE Stewart - Infectious disease clinics of North America, 2008 - Elsevier
The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir
is a variety of small mammals. Although infection of these natural hosts does not lead to …

OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

U Pal, X Yang, M Chen, LK Bockenstedt… - The Journal of …, 2004 - Am Soc Clin Investig
Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of
Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes …