Notch signaling in development, tissue homeostasis, and disease
C Siebel, U Lendahl - Physiological reviews, 2017 - journals.physiology.org
Notch signaling is an evolutionarily highly conserved signaling mechanism, but in contrast to
signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs …
signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs …
Notch signalling in context
SJ Bray - Nature reviews Molecular cell biology, 2016 - nature.com
The highly conserved Notch signalling pathway functions in many different developmental
and homeostatic processes, which raises the question of how this pathway can achieve …
and homeostatic processes, which raises the question of how this pathway can achieve …
Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
Transitions between epithelial and mesenchymal phenotypes–the epithelial to
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …
Precision medicine for human cancers with Notch signaling dysregulation
M Katoh, M Katoh - International journal of molecular …, 2020 - spandidos-publications.com
Abstract NOTCH1, NOTCH2, NOTCH3 and NOTCH4 are transmembrane receptors that
transduce juxtacrine signals of the delta‑like canonical Notch ligand (DLL) 1, DLL3, DLL4 …
transduce juxtacrine signals of the delta‑like canonical Notch ligand (DLL) 1, DLL3, DLL4 …
Mechanisms of Notch signaling: a simple logic deployed in time and space
D Henrique, F Schweisguth - Development, 2019 - journals.biologists.com
Most cells in our body communicate during development and throughout life via Notch
receptors and their ligands. Notch receptors relay information from the cell surface to the …
receptors and their ligands. Notch receptors relay information from the cell surface to the …
Mutations in NOTCH1 cause Adams-Oliver syndrome
AB Stittrich, A Lehman, DL Bodian, J Ashworth… - The American Journal of …, 2014 - cell.com
Notch signaling determines and reinforces cell fate in bilaterally symmetric multicellular
eukaryotes. Despite the involvement of Notch in many key developmental systems, human …
eukaryotes. Despite the involvement of Notch in many key developmental systems, human …
Understanding the principles of pattern formation driven by notch signaling by integrating experiments and theoretical models
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides
regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the …
regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the …
[HTML][HTML] Do as I say, Not (ch) as I do: Lateral control of cell fate
M Sjöqvist, ER Andersson - Developmental biology, 2019 - Elsevier
Breaking symmetry in populations of uniform cells, to induce adoption of an alternative cell
fate, is an essential developmental mechanism. Similarly, domain and boundary …
fate, is an essential developmental mechanism. Similarly, domain and boundary …
Jagged–Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype
Notch signaling pathway mediates cell-fate determination during embryonic development,
wound healing, and tumorigenesis. This pathway is activated when the ligand Delta or the …
wound healing, and tumorigenesis. This pathway is activated when the ligand Delta or the …
Sensory hair cell development and regeneration: similarities and differences
PJ Atkinson, E Huarcaya Najarro, ZN Sayyid… - …, 2015 - journals.biologists.com
Sensory hair cells are mechanoreceptors of the auditory and vestibular systems and are
crucial for hearing and balance. In adult mammals, auditory hair cells are unable to …
crucial for hearing and balance. In adult mammals, auditory hair cells are unable to …