Surface-initiated polymer brushes in the biomedical field: applications in membrane science, biosensing, cell culture, regenerative medicine and antibacterial coatings

M Krishnamoorthy, S Hakobyan, M Ramstedt… - Chemical …, 2014 - ACS Publications
Understanding and controlling interfaces has proven to be key to a very wide range of
applications, from optical and electronic materials 1, 2 to energy storage and production, 3 …

Targeting neutrophils using novel drug delivery systems in chronic respiratory diseases

DK Chellappan, LW Yee, KY Xuan… - Drug development …, 2020 - Wiley Online Library
Neutrophils are essential effector cells of immune system for clearing the extracellular
pathogens during inflammation and immune reactions. Neutrophils play a major role in …

Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

Q Wu, Z He, X Wang, Q Zhang, Q Wei, S Ma… - Nature …, 2019 - nature.com
As the first line of innate immune cells to migrate towards tumour tissue, neutrophils, can
immediately kill abnormal cells and activate long-term specific adaptive immune responses …

Co-immobilization of Cellulase and β-Glucosidase into Mesoporous Silica Nanoparticles for the Hydrolysis of Cellulose Extracted from Eriobotrya japonica Leaves

G Pota, A Sapienza Salerno, A Costantini, B Silvestri… - Langmuir, 2022 - ACS Publications
Fungal cellulases generally contain a reduced amount of β-glucosidase (BG), which does
not allow for efficient cellulose hydrolysis. To address this issue, we implemented an easy co …

Dual-Enzyme-Loaded Multifunctional Hybrid Nanogel System for Pathological Responsive Ultrasound Imaging and T2-Weighted Magnetic Resonance Imaging

X Wang, D Niu, P Li, Q Wu, X Bo, B Liu, S Bao, T Su… - ACS …, 2015 - ACS Publications
A dual-enzyme-loaded multifunctional hybrid nanogel probe (SPIO@ GCS/acryl/biotin-
CAT/SOD-gel, or SGC) has been developed for dual-modality pathological responsive …

Magnetic field remotely controlled selective biocatalysis

A Zakharchenko, N Guz, AM Laradji, E Katz, S Minko - Nature Catalysis, 2018 - nature.com
Many applications for medical therapy, biotechnology and biosensors rely on efficient
delivery and release of active substances. Here, we demonstrate a platform that explores …

Enzyme immobilization on graphite oxide (GO) surface via one-pot synthesis of GO/metal–organic framework composites for large-substrate biocatalysis

J Farmakes, I Schuster, A Overby… - … applied materials & …, 2020 - ACS Publications
Although enzyme immobilization has improved many areas, biocatalysis involving large-size
substrates is still challenging for immobilization platform design because of the protein …

Magnetic nanomaterials as biocatalyst carriers for biomass processing: Immobilization strategies, reusability, and applications

MA Mariño, S Fulaz, L Tasic - Magnetochemistry, 2021 - mdpi.com
Environmental concerns, along with oil shortages, have increased industrial interest in
biomass conversion to produce biofuels and other valuable chemicals. A green option in …

An efficient nano-biocatalyst for lignocellulosic biomass hydrolysis: Xylanase immobilization on organically modified biogenic mesoporous silica nanoparticles

S Ariaeenejad, F Jokar, P Hadian, L Ma'mani… - International Journal of …, 2020 - Elsevier
A biogenic mesoporous silica nanoparticles (MSNs)-based nanocarrier has been used for
improving the stability and recyclability of PersiXyn2 as a recombinant xylanase enzyme …

Xylanase immobilized on novel multifunctional hyperbranched polyglycerol-grafted magnetic nanoparticles: an efficient and robust biocatalyst

A Landarani-Isfahani, A Taheri-Kafrani, M Amini… - Langmuir, 2015 - ACS Publications
Although several strategies are now available for immobilization of enzymes to magnetic
nanoparticles for bioapplications, little progresses have been reported on the use of …