Smad transcription factors

J Massagué, J Seoane, D Wotton - Genes & development, 2005 - genesdev.cshlp.org
Smad transcription factors lie at the core of one of the most versatile cytokine signaling
pathways in metazoan biology—the transforming growth factor-β (TGFβ) pathway. Recent …

The role of the MEIS homeobox genes in neuroblastoma

D Geerts, N Schilderink, G Jorritsma, R Versteeg - Cancer letters, 2003 - Elsevier
We recently found amplification of the TALE homeobox gene MEIS1 in the IMR32
neuroblastoma cell line. We now demonstrate high-level expression of the MEIS1 and …

YES1 drives lung cancer growth and progression and predicts sensitivity to dasatinib

I Garmendia, MJ Pajares, F Hermida-Prado… - American journal of …, 2019 - atsjournals.org
Rationale: The characterization of new genetic alterations is essential to assign effective
personalized therapies in non–small cell lung cancer (NSCLC). Furthermore, finding …

Generation of a concise gene panel for outcome prediction in urinary bladder cancer

AP Mitra, V Pagliarulo, D Yang, FM Waldman… - Journal of clinical …, 2009 - ascopubs.org
Purpose This study sought to determine if alterations in molecular pathways could
supplement TNM staging to more accurately predict clinical outcome in patients with …

Genetic alterations in primary cutaneous CD30+ anaplastic large cell lymphoma

X Mao, G Orchard, DM Lillington… - Genes …, 2003 - Wiley Online Library
Primary cutaneous CD30+ anaplastic large cell lymphoma (C‐ALCL) represents a distinct
clinical subtype of CD30+ anaplastic large cell lymphomas. The etiology and underlying …

YES1 amplification confers trastuzumab–emtansine (T-DM1) resistance in HER2-positive cancer

L Wang, Q Wang, P Xu, L Fu, Y Li, H Fu… - British Journal of …, 2020 - nature.com
Abstract Background Trastuzumab–emtansine (T-DM1), one of the most potent HER2-
targeted drugs, shows impressive efficacy in patients with HER2-positive breast cancers …

Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells

ZM Liu, JT Tseng, DY Hong, HS Huang - Biochemical Journal, 2011 - portlandpress.com
HCC (hepatocellular carcinoma) is among the most common and lethal cancers worldwide
with a poor prognosis mainly due to a high recurrence rate and chemotherapy resistance …

[HTML][HTML] Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA …

L Wang, JS Zhu, MQ Song, GQ Chen… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To study the differential gene expression profiles of target cells in primary gastric
cancer and its metastatic lymph nodes using laser microdissection (LMD) in combination …

Targeted quantitative screening of chromosome 18 encoded proteome in plasma samples of astronaut candidates

AT Kopylov, EV Ilgisonis, AA Moysa… - Journal of Proteome …, 2016 - ACS Publications
This work was aimed at estimating the concentrations of proteins encoded by human
chromosome 18 (Chr 18) in plasma samples of 54 healthy male volunteers (aged 20–47) …

Benzo (a) pyrene promotes migration, invasion and metastasis of lung adenocarcinoma cells by upregulating TGIF

H Yang, H Zhang, T Pan, H Wang, Y Wang - Toxicology Letters, 2018 - Elsevier
This study aimed to investigate the potential roles of TG-interacting factor (TGIF) in benzo (a)
pyrene (BaP)-induced migration, invasion, and metastasis of lung adenocarcinoma cells …