Control of stem cell fate by physical interactions with the extracellular matrix

F Guilak, DM Cohen, BT Estes, JM Gimble, W Liedtke… - Cell stem cell, 2009 - cell.com
A diverse array of environmental factors contributes to the overall control of stem cell activity.
In particular, new data continue to mount on the influence of the extracellular matrix (ECM) …

Physical cues of biomaterials guide stem cell differentiation fate

A Higuchi, QD Ling, Y Chang, ST Hsu… - Chemical …, 2013 - ACS Publications
Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

Mechanical stretching for tissue engineering: two-dimensional and three-dimensional constructs

BD Riehl, JH Park, IK Kwon, JY Lim - Tissue Engineering Part B …, 2012 - liebertpub.com
Mechanical cell stretching may be an attractive strategy for the tissue engineering of
mechanically functional tissues. It has been demonstrated that cell growth and differentiation …

Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation

TM Maul, DW Chew, A Nieponice, DA Vorp - Biomechanics and modeling …, 2011 - Springer
Mesenchymal stem cell (MSC) therapy has demonstrated applications in vascular
regenerative medicine. Although blood vessels exist in a mechanically dynamic …

The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials

X Hu, SH Park, ES Gil, XX Xia, AS Weiss, DL Kaplan - Biomaterials, 2011 - Elsevier
The interactions of C2C12 myoblasts and human bone marrow stem cells (hMSCs) with silk-
tropoelastin biomaterials, and the capacity of each to promote attachment, proliferation, and …

Advances in vascular tissue engineering using protein-based biomaterials

JP Stegemann, SN Kaszuba, SL Rowe - Tissue engineering, 2007 - liebertpub.com
The clinical need for improved blood vessel substitutes, especially in small-diameter
applications, drives the field of vascular tissue engineering. The blood vessel has a well …

[HTML][HTML] Mesenchymal stem cell responses to mechanical stimuli

RM Delaine-Smith, GC Reilly - Muscles, ligaments and tendons …, 2012 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have the potential to replace or restore the function of
damaged tissues and offer much promise in the successful application of tissue engineering …

Development of a tissue-engineered vascular graft combining a biodegradable scaffold, muscle-derived stem cells and a rotational vacuum seeding technique

A Nieponice, L Soletti, J Guan, BM Deasy, J Huard… - Biomaterials, 2008 - Elsevier
There is a clinical need for a tissue-engineered vascular graft (TEVG), and combining stem
cells with biodegradable tubular scaffolds appears to be a promising approach. The goal of …

In Vivo Assessment of a Tissue-Engineered Vascular Graft Combining a Biodegradable Elastomeric Scaffold and Muscle-Derived Stem Cells in a Rat Model

A Nieponice, L Soletti, J Guan, Y Hong… - … Engineering Part A, 2010 - liebertpub.com
Limited autologous vascular graft availability and poor patency rates of synthetic grafts for
bypass or replacement of small-diameter arteries remain a concern in the surgical …

Mesenchymal stem cells for vascular regeneration

NF Huang, S Li - Regenerative medicine, 2008 - Taylor & Francis
Mesenchymal stem cells (MSCs) have tremendous potential for regenerative medicine, and
have been researched for the treatment of cardiovascular diseases. MSCs are a promising …