Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Scorpion venom: detriments and benefits

S Ahmadi, JM Knerr, L Argemi, KCF Bordon, MB Pucca… - Biomedicines, 2020 - mdpi.com
Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …

Antimicrobial and amyloidogenic activity of peptides. Can antimicrobial peptides be used against SARS-CoV-2?

SR Kurpe, SY Grishin, AK Surin, AV Panfilov… - International Journal of …, 2020 - mdpi.com
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …

Antimicrobial activity developed by scorpion venoms and its peptide component

CA Rincón-Cortés, MA Bayona-Rojas… - Toxins, 2022 - mdpi.com
Microbial infections represent a problem of great importance at the public health level, with a
high rate of morbidity-mortality worldwide. However, treating the different diseases …

Scorpion venom as a source of antimicrobial peptides: overview of biomolecule separation, analysis and characterization methods

S Nasr, A Borges, C Sahyoun, R Nasr, R Roufayel… - Antibiotics, 2023 - mdpi.com
Scorpion venoms have long captivated scientific researchers, primarily due to the potency
and specificity of the mechanism of action of their derived components. Among other …

Bioactive peptides from scorpion venoms: therapeutic scaffolds and pharmacological tools

KP Muiruri, J Zhong, YAO Bing, LAI Ren… - Chinese Journal of …, 2023 - Elsevier
Evolution and natural selection have endowed animal venoms, including scorpion venoms,
with a wide range of pharmacological properties. Consequently, scorpions, their venoms …

A critical review of short antimicrobial peptides from scorpion venoms, their physicochemical attributes, and potential for the development of new drugs

PA Fong-Coronado, V Ramirez… - The Journal of …, 2024 - Springer
Scorpion venoms have proven to be excellent sources of antimicrobial agents. However,
although many of them have been functionally characterized, they remain underutilized as …

[HTML][HTML] Structure, function and mechanistic aspects of scorpion venom peptides-A boon for the development of novel therapeutics

R Suhas - European journal of medicinal chemistry reports, 2022 - Elsevier
Venom of scorpions is very expensive and lethal, yet with innumerable and exciting potential
as a source for the development of biotherapeutics. One of the chief components of scorpion …

[HTML][HTML] In silico and in vitro structure–activity relationship of Mastoparan and its analogs

P Rungsa, S Peigneur, N Jangpromma… - Molecules, 2022 - mdpi.com
Antimicrobial peptides are an important class of therapeutic agent used against a wide
range of pathogens such as Gram-negative and Gram-positive bacteria, fungi, and viruses …

[HTML][HTML] Biomedical applications of synthetic peptides derived from venom of animal origin: A systematic review

JL Diaz-Gomez, I Martin-Estal, E Rivera-Aboytes… - Biomedicine & …, 2024 - Elsevier
Abstract Development of therapeutic agents that have fewer adverse effects and have higher
efficacy for diseases, such as cancer, metabolic disorders, neurological diseases, infections …