The role of metabolism in tumor growth and chemoresistance has received considerable
attention, however, the contribution of mitochondrial bioenergetics in migration, invasion …

Platelets are anucleated cell elements produced by fragmentation of the cytoplasm of
megakaryocytes and have a unique metabolic phenotype compared with circulating …

Introduction The use of triphenylphosphonium cation (TPP+) linked to phenolic compounds
by alkyl chains has a significant relevance as a mitochondrial delivery strategy in …

Platelet activation plays an essential role in the pathogenesis of thrombotic events in
different diseases (eg, cancer, type 2 diabetes, Alzheimer's, and cardiovascular diseases …

Highly malignant triple-negative breast cancer (TNBC) cells rely mostly on glycolysis to
maintain cellular homeostasis; however, mitochondria are still required for migration and …

Mitochondrial Complex I plays a crucial role in the proliferation, chemoresistance, and
metastasis of breast cancer (BC) cells. This highlights it as an attractive target for anti-cancer …

The mitochondrion has emerged as a promising therapeutic target for novel cancer
treatments because of its essential role in tumorigenesis and resistance to chemotherapy …

Cardiovascular diseases are the leading cause of death in the world. Platelets have a major
role in cardiovascular events as they bind to the damaged endothelium activating and …

Bothorps atrox is responsible for most of the ophidism cases in Perú. As part of the
envenoming, myotoxicity is one of the most recurrent and destructive effects. In this study, a …

Since breast cancer (BC) cells are dependent on mitochondrial bioenergetics for promoting
proliferation, survival, and metastasis, mitochondria highlight as an important target for …