Current approaches and challenges for the metabolite profiling of complex natural extracts
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …
research. Obtaining precise information on the chemical composition of complex natural …
Endophytic Penicillium species and their agricultural, biotechnological, and pharmaceutical applications
RMK Toghueo, FF Boyom - 3 Biotech, 2020 - Springer
Penicillium genus constituted by over 200 species is one of the largest and fascinating
groups of fungi, particularly well established as a source of antibiotics. Endophytic …
groups of fungi, particularly well established as a source of antibiotics. Endophytic …
Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes
BTD Trinh, D Staerk, AK Jäger - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance The 18 plant species investigated in this study have been
used as herbal antidiabetic remedies in Vietnamese traditional medicines. This study aimed …
used as herbal antidiabetic remedies in Vietnamese traditional medicines. This study aimed …
Current status and contemporary approaches to the discovery of antitumor agents from higher plants
G Agarwal, PJB Carcache, EM Addo… - Biotechnology advances, 2020 - Elsevier
Higher plant constituents have afforded clinically available anticancer drugs. These include
both chemically unmodified small molecules and their synthetic derivatives currently used or …
both chemically unmodified small molecules and their synthetic derivatives currently used or …
Mass spectrometry-based technology and workflows for studying the chemistry of fungal endophyte derived bioactive compounds
Bioactive compounds have gained substantial attention in research and have conferred
great advancements in the industrial and pharmacological fields. Highly diverse fungi and …
great advancements in the industrial and pharmacological fields. Highly diverse fungi and …
High-resolution α-amylase assay combined with high-performance liquid chromatography–solid-phase extraction–nuclear magnetic resonance spectroscopy for …
L Okutan, KT Kongstad, AK Jäger… - Journal of agricultural …, 2014 - ACS Publications
Type 2 diabetes affects millions of people worldwide, and new improved drugs or functional
foods containing selective α-amylase inhibitors are needed for improved management of …
foods containing selective α-amylase inhibitors are needed for improved management of …
Recent advances in the applications of Wittig reaction in the total synthesis of natural products containing lactone, pyrone, and lactam as a scaffold
MM Heravi, M Ghanbarian, V Zadsirjan… - Monatshefte für Chemie …, 2019 - Springer
The Wittig reaction enables the synthesis of an alkene from the reaction of an aldehyde or
ketone with the ylide generated from a phosphonium salt. Undoubtedly, its usefulness in the …
ketone with the ylide generated from a phosphonium salt. Undoubtedly, its usefulness in the …
The 3, 4-dioxygenated 5-hydroxy-4-aryl-quinolin-2 (1 H)-one alkaloids. Results of 20 years of research, uncovering a new family of natural products
SO Simonetti, EL Larghi, TS Kaufman - Natural product reports, 2016 - pubs.rsc.org
Covering: up to April 2016 Aspergillus and Penicillium are fungal species known to produce
a high diversity of secondary metabolites, many of them endowed with interesting bioactivity …
a high diversity of secondary metabolites, many of them endowed with interesting bioactivity …
Identification of PTP1B and α-Glucosidase Inhibitory Serrulatanes from Eremophila spp. by Combined use of Dual High-Resolution PTP1B and α-Glucosidase …
SG Wubshet, Y Tahtah, AM Heskes… - Journal of Natural …, 2016 - ACS Publications
According to the International Diabetes Federation, type 2 diabetes (T2D) has reached
epidemic proportions, affecting more than 382 million people worldwide. Inhibition of protein …
epidemic proportions, affecting more than 382 million people worldwide. Inhibition of protein …
Natural 3,4-dihydro-2(1h)-quinolinones- Part II: animal, bacterial, and fungal sources
S Khadem, RJ Marles - Natural Product Research, 2024 - Taylor & Francis
While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …
potential as lead compounds has been hindered by challenges such as limited accessibility …