Quantitative reflection interference contrast microscopy (RICM) in soft matter and cell adhesion

L Limozin, K Sengupta - ChemPhysChem, 2009 - Wiley Online Library
Adhesion can be quantified by measuring the distance between the interacting surfaces.
Reflection interference contrast microscopy (RICM), with its ability to measure inter‐surface …

Early T cell activation: integrating biochemical, structural, and biophysical cues

B Malissen, P Bongrand - Annual review of immunology, 2015 - annualreviews.org
T cells carry out the formidable task of identifying small numbers of foreign antigenic
peptides rapidly and specifically against a very noisy environmental background of …

Optical measurement of cell membrane tension

G Popescu, T Ikeda, K Goda, CA Best-Popescu… - Physical review …, 2006 - APS
Using a novel noncontact technique based on optical interferometry, we quantify the
nanoscale thermal fluctuations of red blood cells (RBCs) and giant unilamellar vesicles …

On the origin of shape fluctuations of the cell nucleus

FY Chu, SC Haley, A Zidovska - Proceedings of the …, 2017 - National Acad Sciences
The nuclear envelope (NE) presents a physical boundary between the cytoplasm and the
nucleoplasm, sandwiched in between two highly active systems inside the cell: cytoskeleton …

[HTML][HTML] Measuring shape fluctuations in biological membranes

C Monzel, K Sengupta - Journal of Physics D: Applied Physics, 2016 - iopscience.iop.org
Shape fluctuations of lipid membranes have intrigued cell biologists and physicists alike. In
the cellular context, their origin—thermal or active—and their physiological significance are …

Membrane fluctuations mediate lateral interaction between cadherin bonds

SF Fenz, T Bihr, D Schmidt, R Merkel, U Seifert… - Nature physics, 2017 - nature.com
The integrity of living tissues is maintained by adhesion domains of trans-bonds formed
between cadherin proteins residing on opposing membranes of neighbouring cells. These …

[HTML][HTML] Physics of cell adhesion: some lessons from cell-mimetic systems

E Sackmann, AS Smith - Soft matter, 2014 - pubs.rsc.org
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of
material properties and biological functions of cells. It is controlled by competition of short …

Mechanotransduction as a major driver of cell behaviour: Mechanisms, and relevance to cell organization and future research

PH Puech, P Bongrand - Open Biology, 2021 - royalsocietypublishing.org
How do cells process environmental cues to make decisions? This simple question is still
generating much experimental and theoretical work, at the border of physics, chemistry and …

Quantitative phase imaging of nanoscale cell structure and dynamics

G Popescu - Methods in cell biology, 2008 - Elsevier
Quantitative phase imaging (QPI) of live cells has received significant scientific interest over
the past decade or so, mainly because it offers structure and dynamics information at the …

[HTML][HTML] How cells tiptoe on adhesive surfaces before sticking

A Pierres, AM Benoliel, D Touchard, P Bongrand - Biophysical Journal, 2008 - cell.com
Cell membranes are studded with protrusions that were thoroughly analyzed with electron
microscopy. However, the nanometer-scale three-dimensional motions generated by cell …