A review on evaluation of technetium-99m labeled radiopharmaceuticals

MU Akbar, MR Ahmad, A Shaheen… - Journal of Radioanalytical …, 2016 - Springer
In the past few years, substantial progress has been made in technetium chemistry,
including the synthesis of a variety of 99m Tc-radiopharmaceuticals. This synthesis can be …

Novel hydrazide-hydrazone and amide substituted coumarin derivatives: Synthesis, cytotoxicity screening, microarray, radiolabeling and in vivo pharmacokinetic …

T Nasr, S Bondock, HM Rashed, W Fayad… - European journal of …, 2018 - Elsevier
The current work presents the synthesis and biological evaluation of new series of coumarin
hydrazide-hydrazone derivatives that showed in vitro broad spectrum antitumor activities …

Preparation of 99mTc-levetiracetam intranasal microemulsion as the first radiotracer for SPECT imaging of the Synaptic Vesicle Protein SV2A

HM Rashed, RN Shamma, HA El-Sabagh - European Journal of …, 2018 - Elsevier
Selective receptors imaging using gamma emitting radiopharmaceuticals allows accurate
diagnosis and follow up of many brain related disorders. Levetiracetam, a selective SV2A …

Synthesis, quality control, and bio‐evaluation of 99mTc‐cyclophosphamide

TH Bokhari, S Roohi, S Hina, MU Akbar… - Chemical Biology & …, 2018 - Wiley Online Library
Cancer is found to be the leading cause of death worldwide characterized by uncontrolled
cell division. Nuclear medicines imaging using radiopharmaceuticals have pronounced …

Preparation, chromatographic evaluation and biodistribution of 99mTc-procainamide as a radiopharmaceutical for heart imaging

MA Motaleb, IT Ibrahim, RS Abo Rizq… - Radiochimica …, 2017 - degruyter.com
Abstract Procainamide (4-amino-N-[2-(diethylamino) ethyl] benzamide) is a sodium channel
blocker, which acts as an effective antiarrhythmic agent used in the treatment of a variety of …

Synthesis, development and preclinical study of EDDA based 99mTc-5-fluorouracil for brain imaging

N Ahmed, AM Saeed, S Fatima, N Zia, A Raza… - … of Radioanalytical and …, 2016 - Springer
Fluorouracil is used as an antineoplastic agent in solid tumors. The study was conducted to
analyze the effect of EDDA on synthesis of 5-fluorouracil with 99m Tc. The 99m Tc-5 …

[PDF][PDF] Labeling of epirubicin with technetium-99m: Optimization, biodistribution and scintigraphic imaging in tumor bearing mice.

S Hina, TH Bokhari, S Roohi, MI Rajoka… - Pakistan Journal of …, 2018 - academia.edu
Epirubicin is an antineoplastic agent of anthracycline antibiotic, used for treating a variety of
tumor types such as lymphoma, cancer of the breast, lung, ovary and stomach. The objective …

Synthesis and Altered Biodistribution of 99mTc Labeled Vincristine in Animal Model

N Ahmed, A Saeed, S Fatima, M Zia… - Current Medical …, 2018 - ingentaconnect.com
Introduction: Vincristine sulphate is an antineoplastic agent, used in combination for the
chemotherapyof B-cell neoplasm and acute lymphoblastic leukemia. Our aim was to label …