The global COVID-19 pandemic has the potential to severely affect those with rheumatic
diseases or who are taking immunosuppressive therapies. Information is lacking as to how …

Peptidylarginine deiminases (PADs) have an important role in the pathogenesis of
rheumatoid arthritis (RA) owing to their ability to generate citrullinated proteins—the …

Concerns that airborne microplastics (MP) may be detrimental to human health are rising.
However, research on the effects of MP on the respiratory system are limited. We tested the …

Citrullination is a posttranslational modification of arginine catalyzed by five peptidylarginine
deiminases (PADs) in humans. The loss of a positive charge may cause structural or …

Citrullination of joint proteins by the protein arginine deiminase (PAD) family of enzymes is
recognized increasingly as a key process in the pathogenesis of rheumatoid arthritis. This …

The classical autoimmunity paradigm in rheumatoid arthritis (RA) is strongly supported by
immunogenetics suggesting follicular helper T-cell responses driving high titre specific …

Citrullination, the post-translational conversion of arginines to citrullines, may contribute to
rheumatoid arthritis development given the generation of anti-citrullinated protein antibodies …

Neutrophil extracellular traps (NETs) are known as extracellular fibers networks consisting of
antimicrobial proteins and decondensated chromatin DNA released by activated …

In rheumatoid arthritis, an autoimmune inflammatory arthritis, citrullinated proteins are
targeted by autoantibodies and thus thought to drive disease. Neutrophil extracellular traps …

Lung cancer is one of the most common malignancies. In spite of the progress made in past
decades, further studies to improve current therapy for lung cancer are required …