Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

This review covers recent developments in glycosaminoglycan (GAG) analysis via mass
spectrometry (MS). GAGs participate in a variety of biological functions, including cellular …

Solution nuclear magnetic resonance spectroscopy provides unique opportunities to study
the structure and dynamics of biomolecules in aqueous environments. While spin relaxation …

Glycosylation, the major post‐translational modification of proteins, significantly increases
the diversity of proteoforms. Glycans are involved in a variety of pivotal structural and …

Fourier transform mass spectrometry (FTMS) applications require accurate analysis of
extremely complex mixtures of species in wide mass and charge state ranges. To optimize …

Abstract Human roundabout 1 (hRobo1) is an extracellular receptor glycoprotein that plays
important roles in angiogenesis, organ development, and tumor progression. Interaction …

The presence of solvent vapor in a differential mobility spectrometry (DMS) cell creates a
microsolvating environment that can mitigate complications associated with field-induced …

Biglycan (BGN), a small leucine‐rich repeat proteoglycan, is involved in a variety of
pathological processes including malignant transformation, for which the upregulation of …

Collision-induced unfolding (CIU) uses ion mobility to probe the structures of ions of proteins
and noncovalent complexes as a function of the extent of gas-phase activation prior to …

Glycosaminoglycans (GAGs) are sulfated linear O-glycan chains abundantly expressed in
the extracellular matrix (ECM). Among GAGs, chondroitin sulfate (CS) and dermatan sulfate …