Membrane tension: A challenging but universal physical parameter in cell biology
The plasma membrane separates the interior of cells from the outside environment. The
membrane tension, defined as the force per unit length acting on a cross-section of …
membrane tension, defined as the force per unit length acting on a cross-section of …
A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation
To mediate the degradation of biomacromolecules, lysosomes must traffic towards cargo-
carrying vesicles for subsequent membrane fusion or fission. Mutations of the lysosomal …
carrying vesicles for subsequent membrane fusion or fission. Mutations of the lysosomal …
Pathogenesis, epidemiology, diagnosis and clinical aspects of Smith–Lemli–Opitz syndrome
SE Bianconi, JL Cross, CA Wassif… - Expert opinion on orphan …, 2015 - Taylor & Francis
Introduction: Smith–Lemli–Opitz syndrome (SLOS) is a malformation syndrome inherited in
an autosomal recessive fashion. It is due to a metabolic defect in the conversion of 7 …
an autosomal recessive fashion. It is due to a metabolic defect in the conversion of 7 …
Cholesterol extraction from cell membrane by graphene nanosheets: a computational study
The health risk associated with high cholesterol levels in the human body has motivated
intensive efforts to lower them by using specialized drugs. However, little research has been …
intensive efforts to lower them by using specialized drugs. However, little research has been …
Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes
Cholesterol regulates numerous cellular processes. Depleting its synthesis in skeletal
myofibers induces vacuolization and contraction impairment. However, little is known about …
myofibers induces vacuolization and contraction impairment. However, little is known about …
Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells [S]
In specialized cell types, lysosome-related organelles support regulated secretory pathways,
whereas in nonspecialized cells, lysosomes can undergo fusion with the plasma membrane …
whereas in nonspecialized cells, lysosomes can undergo fusion with the plasma membrane …
Cholesterol alters the dynamics of release in protein independent cell models for exocytosis
Neurons communicate via an essential process called exocytosis. Cholesterol, an abundant
lipid in both secretory vesicles and cell plasma membrane can affect this process. In this …
lipid in both secretory vesicles and cell plasma membrane can affect this process. In this …
OxLDL induces membrane structure rearrangement leading to biomechanics alteration and migration deficiency in macrophage
L Rezende, NF Do Couto, W Fernandes-Braga… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Cholesterol sequestration from plasma membrane has been shown to induce lipid packing
disruption, causing actin cytoskeleton reorganization and polymerization, increasing cell …
disruption, causing actin cytoskeleton reorganization and polymerization, increasing cell …
Effect of LDL Extracted from Human Plasma on Membrane Stiffness in Living Endothelial Cells and Macrophages via Scanning Ion Conductance Microscopy
D Kiseleva, V Kolmogorov, V Cherednichenko… - Cells, 2024 - mdpi.com
Mechanical properties of living cells play a crucial role in a wide range of biological
functions and pathologies, including atherosclerosis. We used low-stress Scanning Ion …
functions and pathologies, including atherosclerosis. We used low-stress Scanning Ion …
Effects of cytoskeletal drugs on actin cortex elasticity
Mechanical properties of cells are known to be influenced by the actin cytoskeleton. In this
article, the action of drugs that interact with the actin cortex is investigated by tether …
article, the action of drugs that interact with the actin cortex is investigated by tether …