Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men

CL Sexton, JS Godwin, MC McIntosh, BA Ruple… - Cells, 2023 - mdpi.com
We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA
responses to one bout of lower load (LL) versus higher load (HL) resistance exercise …

Changes in vastus lateralis fibre cross‐sectional area, pennation angle and fascicle length do not predict changes in muscle cross‐sectional area

BA Ruple, PHC Mesquita, JS Godwin… - Experimental …, 2022 - Wiley Online Library
New Findings What is the central question of this study? Do changes in myofibre cross‐
sectional area, pennation angle and fascicle length predict vastus lateralis whole‐muscle …

Comparisons between skeletal muscle imaging techniques and histology in tracking midthigh hypertrophic adaptations following 10 wk of resistance training

BA Ruple, MA Smith, SC Osburn… - Journal of Applied …, 2022 - journals.physiology.org
This study had two aims. Aim1 was to determine the agreement between midthigh vastus
lateralis (VL) cross-sectional area measured by ultrasound (mCSAUS) versus magnetic …

Molecular predictors of resistance training outcomes in young untrained female adults

MA Smith, CL Sexton, KA Smith… - Journal of Applied …, 2023 - journals.physiology.org
We sought to determine if the myofibrillar protein synthetic (MyoPS) response to a naïve
resistance exercise (RE) bout, or chronic changes in satellite cell number and muscle …

Extracellular matrix content and remodeling markers do not differ in college-aged men classified as higher and lower responders to resistance training

JS Godwin, CL Sexton, NJ Kontos… - Journal of Applied …, 2023 - journals.physiology.org
We determined if skeletal muscle extracellular matrix (ECM) content and remodeling
markers adapted with resistance training or were associated with hypertrophic outcomes …

Proteolytic markers associated with a gain and loss of leg muscle mass with resistance training followed by high‐intensity interval training

JM Michel, JS Godwin, DL Plotkin… - Experimental …, 2023 - Wiley Online Library
We recently reported that vastus lateralis (VL) cross‐sectional area (CSA) increases after 7
weeks of resistance training (RT, 2 days/week), with declines occurring following 7 weeks of …

[HTML][HTML] A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training

MD Roberts, BA Ruple, JS Godwin… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
The skeletal muscle proteome alterations to aging and resistance training have been
reported in prior studies. However, conventional proteomics in skeletal muscle typically …

Relative rDNA copy number is not associated with resistance training-induced skeletal muscle hypertrophy and does not affect myotube anabolism in vitro

JS Godwin, JM Michel, AT Ludlow… - American Journal …, 2024 - journals.physiology.org
Ribosomal DNA (rDNA) copies exist across multiple chromosomes and inter-individual
variation in copy number is speculated to influence the hypertrophic response to resistance …

Peripheral quantitative computed tomography is a valid imaging technique for tracking changes in skeletal muscle cross‐sectional area

BA Ruple, CG Vann, CL Sexton… - Clinical Physiology …, 2024 - Wiley Online Library
Peripheral quantitative computed tomography (pQCT) has recently expanded to quantifying
skeletal muscle, however its validity to determine muscle cross‐sectional area (mCSA) …

[PDF][PDF] Skeletal Muscle DNA Methylation and mRNA Responses to a Bout of Higher versus Lower Load Resistance Exercise in Previously Trained Men. Cells 2023, 12 …

CL Sexton, JS Godwin, MC McIntosh, BA Ruple… - 2023 - academia.edu
We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA
responses to one bout of lower load (LL) versus higher load (HL) resistance exercise …