Membrane proteins are a highly relevant class of biological molecules and comprise∼ 60%
of current drug targets. Before being analyzed by structural, biochemical, and biophysical …

Complex integral membrane proteins, which are embedded in the cell surface lipid bilayer
by multiple transmembrane spanning polypeptides, encompass families of proteins that are …

Pannexin 1 (Panx1) constitutes a large pore channel responsible for the release of
adenosine triphosphate (ATP) from apoptotic cells. Strong evidence indicates that caspase …

Membrane proteins (MPs) are essential components of all biological membranes,
contributing to key cellular functions that include signalling, molecular transport and energy …

Pannexin 1 (PANX1) is a widely expressed large-pore ion channel located in the plasma
membrane of almost all vertebrate cells. It possesses a unique ability to act as a conduit for …

Abstract Surface Plasmon Resonance (SPR) technology, as a powerful analytical tool, plays
a crucial role in the preparation, performance evaluation, and biomedical applications of …

Due to their fundamental biological importance, membrane proteins (MPs) are attractive
targets for drug discovery, with cell surface receptors, transporters, ion channels, and …

Nanodiscs represent a versatile tool for studies of membrane proteins and protein-
membrane interactions under native-like conditions. Multiple variations of the Nanodisc …

Pannexin 1 (Panx1) constitutes a large pore channel responsible for the release of ATP from
apoptotic cells. Strong evidence indicates that caspase-mediated cleavage of the C …

Membrane proteins perform numerous critical functions in the cell, making many of them
primary drug targets. However, their preference for a lipid environment makes them …