The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit
The Drosophila brain contains a relatively simple circuit for forming Pavlovian associations,
yet it achieves many operations common across memory systems. Recent advances have …
yet it achieves many operations common across memory systems. Recent advances have …
[HTML][HTML] Do the right thing: neural network mechanisms of memory formation, expression and update in Drosophila
P Cognigni, J Felsenberg, S Waddell - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Recurrent connectivity is anatomically and functionally prevalent in fly memory
circuits.•Sustained reverberant activity is necessary for memory consolidation.•Feedforward …
circuits.•Sustained reverberant activity is necessary for memory consolidation.•Feedforward …
The connectome of the adult Drosophila mushroom body provides insights into function
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
A connectome of a learning and memory center in the adult Drosophila brain
Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …
Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila
Animals discriminate stimuli, learn their predictive value and use this knowledge to modify
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways
Dopamine plays a central role in motivating and modifying behavior, serving to invigorate
current behavioral performance and guide future actions through learning. Here we examine …
current behavioral performance and guide future actions through learning. Here we examine …
[PDF][PDF] Coordinated and compartmentalized neuromodulation shapes sensory processing in Drosophila
Learned and adaptive behaviors rely on neural circuits that flexibly couple the same sensory
input to alternative output pathways. Here, we show that the Drosophila mushroom body …
input to alternative output pathways. Here, we show that the Drosophila mushroom body …
Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics
To understand the brain, molecular details need to be overlaid onto neural wiring diagrams
so that synaptic mode, neuromodulation and critical signaling operations can be considered …
so that synaptic mode, neuromodulation and critical signaling operations can be considered …
[PDF][PDF] Heterosynaptic plasticity underlies aversive olfactory learning in Drosophila
Although associative learning has been localized to specific brain areas in many animals,
identifying the underlying synaptic processes in vivo has been difficult. Here, we provide the …
identifying the underlying synaptic processes in vivo has been difficult. Here, we provide the …
Dopaminergic neurons write and update memories with cell-type-specific rules
Associative learning is thought to involve parallel and distributed mechanisms of memory
formation and storage. In Drosophila, the mushroom body (MB) is the major site of …
formation and storage. In Drosophila, the mushroom body (MB) is the major site of …