Outcomes in hypoplastic left heart syndrome

MK Metcalf, J Rychik - Pediatric Clinics, 2020 - pediatric.theclinics.com
Congenital heart defects occur in 8 per 1000 live births, with anomalies ranging from minor
septal defects to major structural abnormalities of the great vessels or ventricles. Why focus …

[HTML][HTML] Fetal cardiac interventions: Where do we stand?

KG Friedman, W Tworetzky - Archives of Cardiovascular Diseases, 2020 - Elsevier
Fetal cardiac intervention (FCI) is a novel and evolving technique that allows for in utero
treatment of a subset of congenital heart disease. This review describes the rationale …

Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: the European Association for Cardio-Thoracic Surgery (EACTS) and the …

N Alphonso, A Angelini, DJ Barron… - European Journal of …, 2020 - academic.oup.com
Disclaimer 2020: The EACTS/AEPC Guidelines represent the views of the EACTS and the
AEPC and were produced after careful consideration of the scientific and medical …

Decreased left heart flow in fetal lambs causes left heart hypoplasia and pro-fibrotic tissue remodeling

MS Reuter, DJ Sokolowski, J Javier Diaz-Mejia… - Communications …, 2023 - nature.com
Low blood flow through the fetal left heart is often conjectured as an etiology for hypoplastic
left heart syndrome (HLHS). To investigate if a decrease in left heart flow results in growth …

Socioeconomic status and long-term outcomes in single ventricle heart disease

EM Bucholz, LA Sleeper, CS Goldberg… - …, 2020 - publications.aap.org
BACKGROUND: Low socioeconomic status (SES) has emerged as an important risk factor
for higher short-term mortality and neurodevelopmental outcomes in children with …

Impact of maternal–fetal environment on mortality in children with single ventricle heart disease

JJ Savla, ME Putt, J Huang, S Parry… - Journal of the …, 2022 - Am Heart Assoc
BACKGROUND Children with single ventricle heart disease have significant morbidity and
mortality. The maternal–fetal environment (MFE) may adversely impact outcomes after …

Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: a decision analysis

SS Pickard, JB Wong, EM Bucholz… - … Quality and Outcomes, 2020 - Am Heart Assoc
Background: Fetal aortic valvuloplasty (FAV) may prevent progression of midgestation aortic
stenosis to hypoplastic left heart syndrome. However, FAV has well-established risks, and its …

[HTML][HTML] Hybrid strategy in neonates with ductal-dependent systemic circulation and multiple risk factors

NM Ceneri, MH Desai, A Tongut, M Ozturk… - The Journal of thoracic …, 2022 - Elsevier
Objective The study objective was to analyze outcomes of the hybrid strategy for ductal-
dependent systemic circulation consisting of bilateral pulmonary artery banding with or …

A mouse model of hypoplastic left heart syndrome demonstrating left heart hypoplasia and retrograde aortic arch flow

A Rahman, T DeYoung, LS Cahill… - Disease Models & …, 2021 - journals.biologists.com
In hypoplastic left heart syndrome (HLHS), the mechanisms leading to left heart hypoplasia
and their associated fetal abnormalities are largely unknown. Current animal models have …

Need for routine screening of health-related quality of life in families of young children with complex congenital heart disease

DL Denniss, GF Sholler, DSJ Costa, DS Winlaw… - The Journal of …, 2019 - Elsevier
Objectives To assess health-related quality of life (HRQOL) in families of young children with
complex congenital heart disease (CHD), and identify the demographic, clinical, and …