Obesity and chronic kidney disease

Z Jiang, Y Wang, X Zhao, H Cui… - American Journal …, 2023 - journals.physiology.org
The prevalence of obesity has increased dramatically during the past decades, which has
been a major health problem. Since 1975, the number of people with obesity worldwide has …

Adipose tissue inflammation: linking physiological stressors to disease susceptibility

BJ Bradford, GA Contreras - Annual Review of Animal …, 2024 - annualreviews.org
The study of adipose tissue (AT) is enjoying a renaissance. White, brown, and beige
adipocytes are being investigated in adult animals, and the critical roles of small depots like …

Effects of tirzepatide versus insulin glargine on kidney outcomes in type 2 diabetes in the SURPASS-4 trial: post-hoc analysis of an open-label, randomised, phase 3 …

HJL Heerspink, N Sattar, I Pavo, A Haupt… - The Lancet Diabetes & …, 2022 - thelancet.com
Background In the SURPASS-4 trial, the dual GIP and GLP-1 receptor agonist tirzepatide
reduced HbA 1c concentrations, bodyweight, and blood pressure more than titrated daily …

[HTML][HTML] Steatotic liver disease, MASLD and risk of chronic kidney disease

J Bilson, A Mantovani, CD Byrne, G Targher - Diabetes & metabolism, 2023 - Elsevier
With the rising tide of fatty liver disease related to metabolic dysfunction worldwide, the
association of this common liver disease with chronic kidney disease (CKD) has become …

An overview of chronic kidney disease pathophysiology: The impact of gut dysbiosis and oral disease

S Altamura, D Pietropaoli, F Lombardi, R Del Pinto… - Biomedicines, 2023 - mdpi.com
Chronic kidney disease (CKD) is a severe condition and a significant public health issue
worldwide, carrying the burden of an increased risk of cardiovascular events and mortality …

Renal effects of GLP-1 receptor agonists and tirzepatide in individuals with type 2 diabetes: seeds of a promising future

I Caruso, F Giorgino - Endocrine, 2024 - Springer
Purpose Chronic kidney disease (CKD) is one of the most common complications of type 2
diabetes (T2D), and CKD-related disability and mortality are increasing despite the recent …

Flammulina velutipes Mycorrhizae Attenuate High Fat Diet-Induced Lipid Disorder, Oxidative Stress and Inflammation in the Liver and Perirenal Adipose Tissue of …

Z Luo, Q Gao, Y Li, Y Bai, J Zhang, W Xu, J Xu - Nutrients, 2022 - mdpi.com
Flammulina velutipes (FV) is edible mushroom that has nutritional and medicinal values. FV
mycorrhizae, the by-products of FV, are an abundant source and receive less attention. The …

Epicardial adipose tissue: a potential therapeutic target for cardiovascular diseases

W Fang, S Xie, W Deng - Journal of Cardiovascular Translational …, 2024 - Springer
With increased ageing of the population, cardiovascular disease (CVD) has become the
most important factor endangering human health worldwide. Although the treatment of CVD …

Thromboinflammatory processes at the nexus of metabolic dysfunction and prostate cancer: the emerging role of periprostatic adipose tissue

I AlZaim, A Al-Saidi, SH Hammoud, N Darwiche… - Cancers, 2022 - mdpi.com
Simple Summary As overweight and obesity increase among the population worldwide, a
parallel increase in the number of individuals diagnosed with prostate cancer was observed …

Para-perirenal fat thickness is associated with reduced glomerular filtration rate regardless of other obesity-related indicators in patients with type 2 diabetes mellitus

S Xu, J Ma, Y Zheng, R Ren, W Li, W Zhao, Y Ma… - Plos one, 2023 - journals.plos.org
Purpose To investigate the relationship between estimated glomerular filtration rate (eGFR)
and para-perirenal fat thickness in comparison with other indices of adiposity in type 2 …