Scrapie, an invariably fatal disease of sheep and goats, is a transmissible spongiform
encephalopathy (TSE). The putative infectious agent is the host-encoded prion protein, PrP …

Scrapie is a fatal, neurodegenerative disease of sheep and goats. It is also the earliest
known member in the family of diseases classified as transmissible spongiform …

Functional traits have become important for efficient breeding schemes in the dairy goat and
sheep industries, mainly in Mediterranean countries, due to increased costs of production …

The association between PrP gene variations and scrapie susceptibility was studied in a
single herd of Ionica breed goats. The entire herd comprised 100 animals, 11 of which were …

In sheep, susceptibility to scrapie is mainly influenced by polymorphisms of the PrP gene. In
goats, there are to date few data related to scrapie susceptibility association with PrP gene …

Susceptibility to scrapie in sheep is influenced by polymorphisms of the prion protein (PrP)
gene, whereas no strong association between genetics and scrapie has yet been …

Despite intensive studies on sheep scrapie, a number of questions remain unanswered,
such as the natural mode of transmission and the amount of infectivity which accumulates in …

Transmissible spongiform encephalopaties (TSEs) are fatal neurodegenerative diseases
characterized by the aggregation and accumulation of the misfolded prion protein in the …

In contrast to scrapie in sheep, the genetic basis of susceptibility to scrapie in goats is not
well understood. To study the association of prion protein (PrP) alleles with susceptibility to …

The prion protein-encoding gene (prnp) strongly influences the susceptibility of small
ruminants to transmissible spongiform encephalopathies (TSEs). Hence, selective breeding …