Heme oxygenases (HO) catabolize free heme, that is, iron (Fe) protoporphyrin (IX), into
equimolar amounts of Fe2+, carbon monoxide (CO), and biliverdin. The stress-responsive …

BACKGROUND The clinical consequences of antibodies to red blood cells (RBCs) have
been studied for a century. Most clinically relevant antibodies can be detected by sensitive in …

The major emphasis of this updated version of Practice Parameters for Allergy Diagnostic
Testing is focused on how technological refinements and their validations during the past …

La reacción hemolítica inmediata inmunológica representa la principal causa de muerte por
transfusión. La reacción antígeno-anticuerpo con la subsiguiente hemólisis de los …

Abstract Multicenter trials in Southeast Asia have shown better survival rates among patients
with severe malaria, particularly those with high parasitemia levels, treated with intravenous …

The pathobiology of malaria has been extensively studied in humans but many questions
remain, especially regarding fulminant disease associated with Plasmodium falciparum …

Autoimmune hemolytic anemia (AIHA) is defined as the increased destruction of red blood
cells (RBCs) in the presence of anti-RBC autoantibodies with or without complement …

Background Plasma haptoglobin determination is clinically used as parameter for
haemolysis. To date, however, the influence of the mode of haemolysis (extravascular vs …

Drug allergies are adverse drug reactions mediated by the specific immune system. Despite
characteristic signs (eg, skin rash) that raise awareness for possible drug allergies, they are …

Clinicians commonly encounter patients who report to have drug allergy. In a large part,
such allergy corresponds to adverse drug reactions, which are not immune mediated. The …